Microheterogeneity of Recombinant Antibodies: Analytics and Functional Impact
Sign Up to like & getrecommendations! Published in 2018 at "Biotechnology Journal"
DOI: 10.1002/biot.201700476
Abstract: Antibodies are typical examples of biopharmaceuticals which are composed of numerous, almost infinite numbers of potential molecular entities called variants or isoforms, which constitute the microheterogeneity of these molecules. These variants are generated during biosynthesis… read more here.
Keywords: antibodies analytics; microheterogeneity recombinant; microheterogeneity; biological properties ... See more keywords
Biological potential of polysaccharides extracted from Nostoc colonies for film production – Physical and biological properties
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology Journal"
DOI: 10.1002/biot.202200455
Abstract: Cyanobacteria of the Nostoc genus secrete a number of biologically active compounds, including polysaccharides, which may exhibit antioxidant, antimicrobial, anticancer, and anti‐inflammatory properties. The aim of the study was to investigate the biological properties of… read more here.
Keywords: biological potential; biological properties; film; production ... See more keywords
Synthesis of histidine kinase inhibitors and their biological properties
Sign Up to like & getrecommendations! Published in 2019 at "Medicinal Research Reviews"
DOI: 10.1002/med.21651
Abstract: Infections caused by multidrug‐resistant bacteria represent a significant and ever‐increasing cause of morbidity and mortality. There is thus an urgent need to develop efficient and well‐tolerated antibacterials targeting unique cellular processes. Numerous studies have led… read more here.
Keywords: kinase inhibitors; histidine kinase; inhibitors biological; kinase ... See more keywords
Phenotyping Biological Properties of CTV Isolates.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9558-5_3
Abstract: The protocol described is intended to be used alongside molecular methods in order to reveal the relationship between the genome sequence and the biological properties of a single isolate of Citrus tristeza virus complex (CTV).… read more here.
Keywords: biological properties; biology; phenotyping biological; properties ctv ... See more keywords
Modulation of biological properties by grain refinement and surface modification on titanium surfaces for implant-related infections
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Science"
DOI: 10.1007/s10853-019-03811-2
Abstract: The nanostructured titanium (Ti) obtained by the equal-channel angular pressing (ECAP) has shown great promise as a biomedical implant material over the past few decades. The present work aims to investigate the effect of topographical… read more here.
Keywords: surface; biological properties; titanium; properties grain ... See more keywords
Novel secondary metabolites from endophytic fungi: synthesis and biological properties
Sign Up to like & getrecommendations! Published in 2020 at "Phytochemistry Reviews"
DOI: 10.1007/s11101-020-09672-x
Abstract: Abstract Plant-associated endophytic fungi are rich sources of novel bioactive and structurally diverse secondary metabolites and other natural products. Newly synthesized secondary metabolites of endophytes in terrestrial plants and their biological properties are presented and… read more here.
Keywords: novel secondary; fungi synthesis; metabolites endophytic; endophytic fungi ... See more keywords
Effects of Gamma Radiation Sterilization on the Structural and Biological Properties of Decellularized Corneal Xenografts.
Sign Up to like & getrecommendations! Published in 2019 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2019.07.002
Abstract: To address the shortcomings associated with corneal transplants, substantial efforts have been focused on developing new modalities such as xenotransplantion. Xenogeneic corneas are anatomically and biomechanically similar to the human cornea, yet their applications require… read more here.
Keywords: sterilization; dpc; decellularized corneal; biological properties ... See more keywords
Synthesis, biological properties and structural study of new halogenated azolo[4,5-b]pyridines as inhibitors of CK2 kinase.
Sign Up to like & getrecommendations! Published in 2020 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2020.104502
Abstract: The new halogenated 1H-triazolo[4,5-b]pyridines and 1H-imidazo[4,5-b]pyridines were synthesised as analogues of known CK2 inhibitors: 4,5,6,7-tetrabromo-1H-benzotriazole (TBBt) and 4,5,6,7-tetrabromo-1H-benzimidazole (TBBi). Their influence on the activity of recombinant human CK2α, CK2α' and PIM1 kinases was determined. The… read more here.
Keywords: structural study; properties structural; new halogenated; biological properties ... See more keywords
Biological properties of propolis extracts: Something new from an ancient product.
Sign Up to like & getrecommendations! Published in 2017 at "Chemistry and physics of lipids"
DOI: 10.1016/j.chemphyslip.2017.04.005
Abstract: Natural products are an interesting source of new therapeutics, especially for cancer therapy as 70% of them have botany origin. Propolis, a resinous mixture that honey bees collect and transform from tree buds, sap flows,… read more here.
Keywords: something new; propolis extracts; new ancient; properties propolis ... See more keywords
Monitoring soil biological properties during the restoration of a phosphate mine under different tree species and plantation types.
Sign Up to like & getrecommendations! Published in 2019 at "Ecotoxicology and environmental safety"
DOI: 10.1016/j.ecoenv.2019.05.001
Abstract: Open-pit mining activities for minerals and metals have left an international legacy of highly polluted soils and degraded landscapes. Reforestation is usually supposed to restore soil fertility and ecosystem services, and therefore to remediate and… read more here.
Keywords: plantation types; restoration; biological properties; soil ... See more keywords
Phytochemistry and biological properties of isoprenoid flavonoids from Sophora flavescens Ait.
Sign Up to like & getrecommendations! Published in 2020 at "Fitoterapia"
DOI: 10.1016/j.fitote.2020.104556
Abstract: Sophora flavescens Ait (Ku-Shen in Chinese) is a popular traditional Chinese herbal medicine in China for a long history. It shows significant pharmacological activities in the treatment of dysentery, eczema, fever, jaundice, vulvar swelling, gastrointestinal… read more here.
Keywords: isoprenoid flavonoids; phytochemistry biological; biological properties; sophora flavescens ... See more keywords