Biological therapy downregulates the heterodimer S100A8/A9 (calprotectin) expression in psoriatic patients
Sign Up to like & getrecommendations! Published in 2018 at "Inflammation Research"
DOI: 10.1007/s00011-018-1147-6
Abstract: The pathophysiology of psoriasis is very complex and involves an interplay between immune cells and keratinocytes. The keratinocyte production of calprotectin (S100A8/A9), induced by the inflammatory psoriatic milieu, may be involved in initiating immune cell… read more here.
Keywords: biological therapy; psoriatic patients; s100a8; expression ... See more keywords
Evaluation of the immune response to hepatitis B vaccine in patients on biological therapy: results of the RIER cohort study
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Rheumatology"
DOI: 10.1007/s10067-020-05042-2
Abstract: To evaluate the response to hepatitis B virus (HBV) vaccine in patients on biological therapy. Adults with autoimmune inflammatory diseases on biological therapy such as anti-TNFα, rituximab, tocilizumab, abatacept, or anakinra were included. Hepatitis B… read more here.
Keywords: response; vaccine; biological therapy; patients biological ... See more keywords
COVID-19 in IBD: The experience of a single tertiary IBD center
Sign Up to like & getrecommendations! Published in 2020 at "Digestive and Liver Disease"
DOI: 10.1016/j.dld.2020.12.012
Abstract: BACKGROUND Italy has been one of the most affected countries in the world by COVID-19. There has been increasing concern regarding the impact of COVID‐19 on patients with inflammatory bowel disease (IBD), particularly in patients… read more here.
Keywords: covid ibd; biological therapy; single tertiary; covid ... See more keywords
REDOSER project: optimising biological therapy dose for rheumatoid arthritis and spondyloarthritis patients
Sign Up to like & getrecommendations! Published in 2017 at "Heliyon"
DOI: 10.1016/j.heliyon.2017.e00452
Abstract: Background Reducing the dose of biological therapy (BT) when patients with immune-mediated arthritis achieve a sustained therapeutic goal may help to decrease costs for national health services and reduce the risk of serious infection. However,… read more here.
Keywords: biological therapy; reducing dose; rheumatoid arthritis; spondyloarthritis ... See more keywords
Novel aspects of the activation of NADPH oxidase in neutrophils of rheumatic patients on biological therapy
Sign Up to like & getrecommendations! Published in 2019 at "International Immunopharmacology"
DOI: 10.1016/j.intimp.2019.02.015
Abstract: &NA; The relationship between inflammation and formation of reactive oxygen species (ROS) is still not completely understood and excessive inflammatory reaction is attributed to increased yet also to reduced ROS formation. To compare ROS formation… read more here.
Keywords: rheumatic patients; biological therapy; inflammation; ros ... See more keywords
Biological therapy in chronic rhinosinusitis with nasal polyps
Sign Up to like & getrecommendations! Published in 2025 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2025.2459929
Abstract: ABSTRACT Introduction Chronic rhinosinusitis with nasal polyps (CRSwNP) is a heterogeneous disease. High proportions of patients with CRSwNP characterized by type 2 inflammation fail to gain adequate control with conventional treatment. The application of biologics… read more here.
Keywords: chronic rhinosinusitis; therapy; biological therapy; rhinosinusitis nasal ... See more keywords
P458 Effectiveness of biological therapy for pouchitis and other inflammatory complications ot the pouch. And the question of a second Anti-TNF after failure? Results from the RESERVO Study of GETECCU
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjab076.582
Abstract: Pouchitis and Crohn′s-like disease of the pouch (CDP) can be refractory to conventional therapy. Evidence of biological therapy has been rarely reported in large patient cohorts. We explored the use and effectiveness of these therapies… read more here.
Keywords: biological therapy; therapy; pouchitis; response ... See more keywords
P1211 Factors Associated with the Optimization of Biological Therapy in Crohn's Disease and Ulcerative Colitis: Insights from the National GEDIIB Patient Registry in Brazil
Sign Up to like & getrecommendations! Published in 2025 at "Journal of Crohn's and Colitis"
DOI: 10.1093/ecco-jcc/jjae190.1385
Abstract: Biological therapy has revolutionized the treatment of inflammatory bowel disease (IBD); however, a subset of patients still requires therapy optimization to achieve therapeutic goals. This study aimed to identify patients who underwent biological therapy optimization… read more here.
Keywords: disease; biological therapy; registry; colitis ... See more keywords
Serological Status of Inflammatory Bowel Disease Patients Before Starting Biological Therapy - Data From a Tertiary Centre of the Best Vaccined Country.
Sign Up to like & getrecommendations! Published in 2020 at "Inflammatory bowel diseases"
DOI: 10.1093/ibd/izaa005
Abstract: We have read with great interest the recently published paper by Martinelli et al. about poor immunization status of children with the diagnosis of Inflammatory Bowel Disease (IBD) and about insufficient serological testing before starting… read more here.
Keywords: inflammatory bowel; biological therapy; status; bowel disease ... See more keywords
Early Biological Therapy in Operated Crohn’s Disease Patients Is Associated With a Lower Rate of Endoscopic Recurrence and Improved Long-term Outcomes: A Single-center Experience
Sign Up to like & getrecommendations! Published in 2022 at "Inflammatory Bowel Diseases"
DOI: 10.1093/ibd/izac110
Abstract: Abstract Background Two-thirds of Crohn’s disease (CD) patients require surgery during their disease course. However, surgery is not curative, and endoscopic recurrence is observed in up to 90% of cases. Our aim was to investigate… read more here.
Keywords: disease; therapy; biological therapy; rate ... See more keywords
Potential Predictors of Biological Therapy Intensification in Moderate‐To‐Severe Hidradenitis Suppurativa: A Multicentre Study
Sign Up to like & getrecommendations! Published in 2025 at "Australasian Journal of Dermatology"
DOI: 10.1111/ajd.14412
Abstract: Moderate‐to‐severe hidradenitis suppurativa (HS) is a debilitating disease that often requires biological therapy. Despite the effectiveness of approved doses, some patients experience partial or loss of response over time, leading to the need for dose… read more here.
Keywords: moderate severe; therapy; biological therapy; hidradenitis suppurativa ... See more keywords