Well-designed two-fold crosslinked biological valve leaflets with heparin-loaded hydrogel coating for enhancing anticoagulation, endothelialization, and anticalcification.
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DOI: 10.1039/d2bm00736c
Abstract: Commercial biological valve leaflets (BVLs) crosslinked with glutaraldehyde (GA) are at risk of accelerating damage and even failure, owing to the high cell toxicity of GA, acute thrombosis, and calcification in clinical applications. In this… read more here.
Keywords: biological valve; hydrogel coating; hydrogel; heparin loaded ... See more keywords