Chemical Biology Approaches to Understanding Neuronal O–GlcNAcylation
Sign Up to like & getrecommendations! Published in 2022 at "Israel journal of chemistry"
DOI: 10.1002/ijch.202200071
Abstract: O-linked β-N-acetylglucosamine (O–GlcNAc) is a ubiquitous post-translational modification in mammals, decorating thousands of intracellular proteins. O–GlcNAc cycling is an essential regulator of myriad aspects of cell physiology and is dysregulated in numerous human diseases. Notably,… read more here.
Keywords: neuronal glcnacylation; chemical biology; biology approaches; biology ... See more keywords
Evolving Schema for Employing Network Biology Approaches to Understand Pulmonary Hypertension.
Sign Up to like & getrecommendations! Published in 2021 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-63046-1_4
Abstract: Reductionist approaches have served as the cornerstone for traditional mechanistic endeavors in biomedical research. However, for pulmonary hypertension (PH), a relatively rare but deadly vascular disease of the lungs, the use of traditional reductionist approaches… read more here.
Keywords: biology approaches; network; pulmonary hypertension; disease ... See more keywords
Controlling biofilms using synthetic biology approaches.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2020.107518
Abstract: Bacterial biofilms are formed by the complex but ordered regulation of intra- or inter-cellular communication, environmentally responsive gene expression, and secretion of extracellular polymeric substances. Given the robust nature of biofilms due to the non-growing… read more here.
Keywords: controlling biofilms; biology approaches; synthetic biology; using synthetic ... See more keywords
Experimental systems biology approaches reveal interaction mechanisms in model multispecies communities.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in microbiology"
DOI: 10.1016/j.tim.2021.03.012
Abstract: Interactions between microorganisms in multispecies communities are thought to have substantial consequences for the community. Identifying the molecules and genetic pathways that contribute to such interplay is thus crucial to understand as well as modulate… read more here.
Keywords: biology approaches; experimental systems; approaches reveal; multispecies communities ... See more keywords
Synthetic biology approaches to establish a heterologous production system for coronatines.
Sign Up to like & getrecommendations! Published in 2017 at "Metabolic engineering"
DOI: 10.1016/j.ymben.2017.09.009
Abstract: Coronatine (COR) represents a phytotoxin produced by several pathovars of Pseudomonas syringae. It mediates multiple virulence activities by mimicking the plant stress hormone jasmonoyl-l-isoleucine. Structurally, COR consists of a bicyclic polyketide moiety, coronafacic acid (CFA),… read more here.
Keywords: biology approaches; production; cor; synthetic biology ... See more keywords
Synthetic biology approaches for the production of plant metabolites in unicellular organisms.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of experimental botany"
DOI: 10.1093/jxb/erx119
Abstract: Synthetic biology is the repurposing of biological systems for novel objectives and applications. Through the co-ordinated and balanced expression of genes, both native and those introduced from other organisms, resources within an industrial chassis can… read more here.
Keywords: biology approaches; production; plant; synthetic biology ... See more keywords
Synthetic biology approaches for improving photosynthesis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/erz029
Abstract: We discuss current efforts to boost plant carbon fixation using a synthetic biology approach, highlighting the engineering of Rubisco, optimizing the Calvin cycle, introducing carbon-concentrating mechanisms, and rewiring photorespiration. read more here.
Keywords: botany; biology approaches; synthetic biology; approaches improving ... See more keywords
Bioinformatics and systems biology approaches to identify the effects of COVID-19 on neurodegenerative diseases: A review
Sign Up to like & getrecommendations! Published in 2022 at "Medicine"
DOI: 10.1097/md.0000000000032100
Abstract: Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), causing coronavirus disease (COVID-19), has been devastated by COVID-19 in an increasing number of countries and health care systems around the world since its announcement of a global… read more here.
Keywords: systems biology; disease; biology approaches; bioinformatics systems ... See more keywords
Systems biology approaches to understand the effects of nutrition and promote health.
Sign Up to like & getrecommendations! Published in 2017 at "British journal of clinical pharmacology"
DOI: 10.1111/bcp.12965
Abstract: Within the last years the implementation of systems biology in nutritional research has emerged as a powerful tool to understand the mechanisms by which dietary components promote health and prevent disease as well as to… read more here.
Keywords: biology approaches; approaches understand; promote health; biology ... See more keywords
Attenuation of a Pathogenic Mycoplasma Strain by Modification of the obg Gene by Using Synthetic Biology Approaches
Sign Up to like & getrecommendations! Published in 2019 at "mSphere"
DOI: 10.1128/msphere.00030-19
Abstract: Animal diseases due to mycoplasmas are a major cause of morbidity and mortality associated with economic losses for farmers all over the world. Currently used mycoplasma vaccines exhibit several drawbacks, including low efficacy, short time… read more here.
Keywords: synthetic biology; phenotype; biology; mycoplasma ... See more keywords
Systems Biology Approaches Toward Understanding Primary Mitochondrial Diseases
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Genetics"
DOI: 10.3389/fgene.2019.00019
Abstract: Primary mitochondrial diseases form one of the most common and severe groups of genetic disease, with a birth prevalence of at least 1 in 5000. These disorders are multi-genic and multi-phenotypic (even within the same… read more here.
Keywords: biology approaches; mitochondrial diseases; generation; primary mitochondrial ... See more keywords