A Chemical Biology Solution to Problems with Studying Biologically Important but Unstable 9-O-Acetyl Sialic Acids.
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DOI: 10.1021/acschembio.6b00928
Abstract: 9-O-Acetylation is a common natural modification on sialic acids (Sias) that terminate many vertebrate glycan chains. This ester group has striking effects on many biological phenomena, including microbe-host interactions, complement action, regulation of immune responses,… read more here.
Keywords: acetyl; chemical biology; sialic acids; group ... See more keywords