Chemical Biology Tools To Investigate Malaria Parasites
Sign Up to like & getrecommendations! Published in 2021 at "Chembiochem"
DOI: 10.1002/cbic.202000882
Abstract: Parasitic diseases like malaria tropica have been shaping human evolution and history since the beginning of mankind. After infection, the response of the human host ranges from asymptomatic to severe and may culminate in death.… read more here.
Keywords: chemical biology; investigate malaria; biology tools; biology ... See more keywords
Chemical biology tools for probing transcytosis at the blood–brain barrier† †Electronic supplementary information (ESI) available. See DOI: 10.1039/c9sc04024b
Sign Up to like & getrecommendations! Published in 2019 at "Chemical Science"
DOI: 10.1039/c9sc04024b
Abstract: A BBB vehicle library is validated, establishing a SAR for uptake. Merging AMT/RMT motifs chemoselectively increased permeability. read more here.
Keywords: chemical biology; biology tools; chemical; biology ... See more keywords
Molecular Epigenetics: Chemical Biology Tools Come of Age.
Sign Up to like & getrecommendations! Published in 2021 at "Annual review of biochemistry"
DOI: 10.1146/annurev-biochem-080120-021109
Abstract: The field of epigenetics has exploded over the last two decades, revealing an astonishing level of complexity in the way genetic information is stored and accessed in eukaryotes. This expansion of knowledge, which is very… read more here.
Keywords: chemical biology; chemistry; epigenetics chemical; biology tools ... See more keywords
Deciphering the Structure and Formation of Amyloids in Neurodegenerative Diseases With Chemical Biology Tools
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Chemistry"
DOI: 10.3389/fchem.2022.886382
Abstract: Protein aggregation into highly ordered, regularly repeated cross-β sheet structures called amyloid fibrils is closely associated to human disorders such as neurodegenerative diseases including Alzheimer’s and Parkinson’s diseases, or systemic diseases like type II diabetes.… read more here.
Keywords: chemical biology; biology tools; chemistry; formation ... See more keywords
Chemical biology tools to interrogate the roles of O-GlcNAc in immunity
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1089824
Abstract: The O-linked β-N-acetylglucosamine (O-GlcNAc) glycosylation of proteins is an essential and dynamic post-translational modification in mammalian cells that is regulated by the action of two enzymes. O-GlcNAc transferase (OGT) incorporates this monosaccharide on serine/threonine residues,… read more here.
Keywords: chemical biology; interrogate roles; tools interrogate; biology tools ... See more keywords
Synthetic Biology Tools for Novel Secondary Metabolite Discovery in Streptomyces.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of microbiology and biotechnology"
DOI: 10.4014/jmb.1904.04015
Abstract: Streptomyces are attractive microbial cell factories that have industrial capability to produce a wide array of bioactive secondary metabolites. However, the genetic potential of the Streptomyces species has not been fully utilized because most of… read more here.
Keywords: secondary metabolite; novel secondary; synthetic biology; biology tools ... See more keywords