Toward a Point-of-Need Bioluminescence-Based Immunoassay Utilizing a Complete Shelf-Stable Reagent.
Sign Up to like & getrecommendations! Published in 2021 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.0c05074
Abstract: Enzyme-linked immunosorbent assays (ELISAs) are used extensively for the detection and quantification of biomolecules in clinical diagnostics as well as in basic research. Although broadly used, the inherent complexities of ELISAs preclude their utility for… read more here.
Keywords: bioluminescence based; based immunoassay; reagent; point need ... See more keywords
A validated bioluminescence-based assay for the rapid determination of the initial rate of kill for discovery antimalarials
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DOI: 10.1093/jac/dkw449
Abstract: Objectives: A future treatment for uncomplicated malaria will contain at least one component that exerts a rapid rate of kill. We describe here the validation and application of a simple, robust and rapid bioluminescence-based assay… read more here.
Keywords: determination initial; bioluminescence based; rate kill; rate ... See more keywords
A Bioluminescence-Based Drug Screen Identifies Activities of Fexinidazole and Its Metabolites against Helicobacter pylori
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DOI: 10.3390/antibiotics11111605
Abstract: Helicobacter pylori is responsible for a wide range of gastric diseases, including gastric cancer and gastritis. With half of the world’s population infected by H. pylori and the current standard of care associated with suboptimal… read more here.
Keywords: bioluminescence based; fexinidazole metabolites; activities fexinidazole; based drug ... See more keywords