A Bioluminescent Probe for Detecting Norepinephrine in Vivo.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00460
Abstract: As a neurotransmitter, norepinephrine (NE) is critical for psychiatric conditions, neurodegenerative diseases, and pheochromocytoma. A real-time and noninvasive method for the detection of NE as a tracer to investigate the NE-relevant disease treatment process is… read more here.
Keywords: bioluminescent probe; probe detecting; detecting norepinephrine; probe ... See more keywords
Bioluminescent Probe for Monitoring Endogenous Fibroblast Activation Protein Alpha.
Sign Up to like & getrecommendations! Published in 2019 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.9b02117
Abstract: Fibroblast activation protein-α (FAP), as a crucial member of cell surface glycoprotein, highly expresses in reactive fibroblasts of tumors and several fibrosis diseases. It is a potential target for drug design and also reported as… read more here.
Keywords: activation protein; fibroblast activation; bioluminescent probe; probe ... See more keywords
A bioluminescent probe for longitudinal monitoring of mitochondrial membrane potential
Sign Up to like & getrecommendations! Published in 2020 at "Nature Chemical Biology"
DOI: 10.1038/s41589-020-0602-1
Abstract: Mitochondrial membrane potential (Δ Ψ m ) is a universal selective indicator of mitochondrial function and is known to play a central role in many human pathologies, such as diabetes mellitus, cancer and Alzheimer’s and… read more here.
Keywords: longitudinal monitoring; probe; bioluminescent probe; membrane potential ... See more keywords
A sequentially activated bioluminescent probe for observation of cellular H2O2 production induced by cysteine.
Sign Up to like & getrecommendations! Published in 2021 at "Chemical communications"
DOI: 10.1039/d1cc04015d
Abstract: We report herein a caged luciferin probe Cy-Hy as a sequentially activated probe to selectively and sensitively sense L-Cys and H2O2. The probe displayed fluorescence and bioluminescence responses toward the two analytes. Utilizing the present… read more here.
Keywords: probe observation; activated bioluminescent; probe; sequentially activated ... See more keywords
An AND-gate bioluminescent probe for precise tumor imaging
Sign Up to like & getrecommendations! Published in 2023 at "Chemical Science"
DOI: 10.1039/d3sc00556a
Abstract: Sensitivity and specificity are two indispensable requirements to ensure diagnostic accuracy. Dual-locked probes with “AND-gate” logic theory have emerged as a powerful tool to enhance imaging specificity, avoid “false positive” results, and realize correlation analysis.… read more here.
Keywords: tumor; bioluminescent probe; gate bioluminescent; probe precise ... See more keywords