A Blood-Based Biomarker of Cognitive Decline and Interaction With Lifestyle.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.3602
Abstract: Desai et al1 investigated whether engaging in physical activity moderated the association between concentrations of plasma neurofilament light chain (NfL) and cognitive function over time in adults aged 65 years or older who participated in… read more here.
Keywords: biomarker; physical activity; lifestyle factors; activity ... See more keywords
Could Albumin Be a Biomarker to Monitor the Effect of Intravenous Immunoglobulin on Guillain-Barré Syndrome?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2017.0563
Abstract: Could Albumin Be a Biomarker to Monitor the Effect of Intravenous Immunoglobulin on Guillain-Barré Syndrome? To the Editor Fokkink and colleagues1 reported that hypoalbuminemia was associated with a severe clinical course and poor outcomes among… read more here.
Keywords: intravenous immunoglobulin; biomarker; biomarker monitor; albumin biomarker ... See more keywords
Human Epidermal Growth Factor Receptor 2 as a Molecular Biomarker for Metastatic Colorectal Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2017.3323
Abstract: TheAmericanSocietyforClinicalPathologytogetherwith the College of American Pathologists, the Association for Molecular Pathology, and the American Society of Clinical Oncology have recently published a guideline for biomarkers in the evaluation of colorectal cancer (CRC).1 In this article… read more here.
Keywords: biomarker; cancer; metastatic crc; her2 ... See more keywords
MicroRNA‐9 inhibits growth and invasion of head and neck cancer cells and is a predictive biomarker of response to plerixafor, an inhibitor of its target CXCR4
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12352
Abstract: Head and neck squamous cell carcinomas (HNSCC) are associated with poor morbidity and mortality. Current treatment strategies are highly toxic and do not benefit over 50% of patients. There is therefore a crucial need for… read more here.
Keywords: biomarker; hnscc; cell; head neck ... See more keywords
Early circulating tumor DNA dynamics as a pan‐tumor biomarker for long‐term clinical outcome in patients treated with durvalumab and tremelimumab
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13349
Abstract: There is an urgent need to identify biomarkers of early response that can accurately predict the benefit of immune checkpoint inhibitors (ICI). Patients receiving durvalumab/tremelimumab had tumor samples sequenced before treatment (baseline) to identify variants… read more here.
Keywords: circulating tumor; biomarker; tumor; treatment ... See more keywords
CSF Mitochondrial DNA: Biomarker of Body Composition and Energy Metabolism in Parkinson's Disease.
Sign Up to like & getrecommendations! Published in 2025 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.70183
Abstract: Cerebrospinal fluid (CSF) cell‐free mitochondrial DNA (cf‐mtDNA) is a potential biomarker for Parkinson's disease (PD), but its clinical relevance remains unclear. We investigated associations between CSF cf‐mtDNA levels, body composition, nutritional status, and metabolic biomarkers… read more here.
Keywords: body composition; csf; mitochondrial dna; parkinson disease ... See more keywords
Diffusion Tractography Biomarker for Epilepsy Severity in Children With Drug-Resistant Epilepsy.
Sign Up to like & getrecommendations! Published in 2025 at "Annals of clinical and translational neurology"
DOI: 10.1002/acn3.70217
Abstract: OBJECTIVE To develop a novel deep-learning model of clinical DWI tractography that can accurately predict the general assessment of epilepsy severity (GASE) in pediatric drug-resistant epilepsy (DRE) and test if it can screen diverse neurocognitive… read more here.
Keywords: epilepsy; gase; gase scores; biomarker ... See more keywords
Oncofetal MCB1 Is a Functional Biomarker for HCC Personalized Therapy
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202401228
Abstract: Hepatocellular carcinoma (HCC) is one of the leading causes of cancer‐related death worldwide and lacks biomarkers for personalized therapy. Herein, it is reported that MCB1 could be a novel oncofetal protein that is upregulated in… read more here.
Keywords: therapy; hcc; personalized therapy; oncofetal mcb1 ... See more keywords
Cystatin C as Biomarker for the Evaluation of Renal Outcome in AL Amyloidosis
Sign Up to like & getrecommendations! Published in 2025 at "American Journal of Hematology"
DOI: 10.1002/ajh.27716
Abstract: Cystatin C (CysC) has emerged as a novel and potentially more reliable biomarker for the estimation of glomerular filtration in the general population in patients with various conditions. In AL amyloidosis, the current renal staging… read more here.
Keywords: progression; renal outcome; progression dialysis; cysc ... See more keywords
Synaptic Density Reductions in MSA: A Potential Biomarker Identified Through [18F]SynVesT‐1 PET Imaging
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Neurology"
DOI: 10.1002/ana.27179
Abstract: The objective of this study was to delineate synaptic density alterations in multiple system atrophy (MSA) and explore its potential role as a biomarker for MSA diagnosis and disease severity monitoring using [18F]SynVesT‐1 positron emission… read more here.
Keywords: synaptic density; pet; 18f synvest; density reductions ... See more keywords
Dopamine Transporter Imaging as Objective Monitoring Biomarker in Parkinson's Disease
Sign Up to like & getrecommendations! Published in 2025 at "Annals of Neurology"
DOI: 10.1002/ana.27223
Abstract: Although dopamine transporter (DaT) imaging is a valuable diagnostic biomarker, few studies have investigated its utility in objectively monitoring disease progression in patients with Parkinson's disease (PD). To date, no study has established a longitudinal… read more here.
Keywords: disease; transporter imaging; biomarker; parkinson disease ... See more keywords