A Blood-Based Biomarker of Cognitive Decline and Interaction With Lifestyle.
Sign Up to like & getrecommendations! Published in 2022 at "JAMA network open"
DOI: 10.1001/jamanetworkopen.2022.3602
Abstract: Desai et al1 investigated whether engaging in physical activity moderated the association between concentrations of plasma neurofilament light chain (NfL) and cognitive function over time in adults aged 65 years or older who participated in… read more here.
Keywords: biomarker; physical activity; lifestyle factors; activity ... See more keywords
Could Albumin Be a Biomarker to Monitor the Effect of Intravenous Immunoglobulin on Guillain-Barré Syndrome?
Sign Up to like & getrecommendations! Published in 2017 at "JAMA neurology"
DOI: 10.1001/jamaneurol.2017.0563
Abstract: Could Albumin Be a Biomarker to Monitor the Effect of Intravenous Immunoglobulin on Guillain-Barré Syndrome? To the Editor Fokkink and colleagues1 reported that hypoalbuminemia was associated with a severe clinical course and poor outcomes among… read more here.
Keywords: intravenous immunoglobulin; biomarker; biomarker monitor; albumin biomarker ... See more keywords
Human Epidermal Growth Factor Receptor 2 as a Molecular Biomarker for Metastatic Colorectal Cancer.
Sign Up to like & getrecommendations! Published in 2018 at "JAMA oncology"
DOI: 10.1001/jamaoncol.2017.3323
Abstract: TheAmericanSocietyforClinicalPathologytogetherwith the College of American Pathologists, the Association for Molecular Pathology, and the American Society of Clinical Oncology have recently published a guideline for biomarkers in the evaluation of colorectal cancer (CRC).1 In this article… read more here.
Keywords: biomarker; cancer; metastatic crc; her2 ... See more keywords
MicroRNA‐9 inhibits growth and invasion of head and neck cancer cells and is a predictive biomarker of response to plerixafor, an inhibitor of its target CXCR4
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12352
Abstract: Head and neck squamous cell carcinomas (HNSCC) are associated with poor morbidity and mortality. Current treatment strategies are highly toxic and do not benefit over 50% of patients. There is therefore a crucial need for… read more here.
Keywords: biomarker; hnscc; cell; head neck ... See more keywords
Early circulating tumor DNA dynamics as a pan‐tumor biomarker for long‐term clinical outcome in patients treated with durvalumab and tremelimumab
Sign Up to like & getrecommendations! Published in 2022 at "Molecular Oncology"
DOI: 10.1002/1878-0261.13349
Abstract: There is an urgent need to identify biomarkers of early response that can accurately predict the benefit of immune checkpoint inhibitors (ICI). Patients receiving durvalumab/tremelimumab had tumor samples sequenced before treatment (baseline) to identify variants… read more here.
Keywords: circulating tumor; biomarker; tumor; treatment ... See more keywords
Cardiovascular biomarker troponin I biosensor: Aptamer‐gold‐antibody hybrid on a metal oxide surface
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2380
Abstract: Myocardial infarction (MI) is highly related to cardiac arrest leading to death and organ damage. Radiological techniques and electrocardiography have been used as preliminary tests to diagnose MI; however, these techniques are not sensitive enough… read more here.
Keywords: biomarker; surface; gold; troponin ... See more keywords
Development and validation of ELISA for screening of Kratom (Mitragyna speciosa) habitual users using urinary AZ122 biomarker
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.2392
Abstract: Kratom (Mitragyna speciosa Korth) has been used traditionally in Southeast Asia for its therapeutic properties. The major alkaloid of kratom, mitragynine, binds to opioid receptors to give opioid‐like effects that causes addiction. In our previous… read more here.
Keywords: mitragyna speciosa; biomarker; kratom; habitual users ... See more keywords
Elevated homocysteine, as a biomarker of cardiac injury, in panic disorder patients due to oxidative stress
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1851
Abstract: Patients with panic disorder (PD) suffer from elevated oxidative stress as a consequence of serotonin metabolism disorder. These patients have elevated serotonin concentration and catabolism of serotonin via monoamine oxidase. The aim of the present… read more here.
Keywords: biomarker; disorder; panic disorder; disorder patients ... See more keywords
Are the atrial natriuretic peptides a missing link predicting low‐voltage areas in atrial fibrillation? Introducing the novel biomarker‐based atrial fibrillation substrate prediction (ANP) score
Sign Up to like & getrecommendations! Published in 2020 at "Clinical Cardiology"
DOI: 10.1002/clc.23378
Abstract: In patients with atrial fibrillation (AF), left atrial (LA) enlargement, and the presence of low‐voltage areas (LVAs) indicate an advanced disease stage. NT‐proANP is a biomarker, which is significantly higher in both phenotypes. Prediction of… read more here.
Keywords: atrial fibrillation; low voltage; fibrillation; voltage areas ... See more keywords
Implementation of precision medicine in clinical trials in thoracic oncology: Which are the hurdles?
Sign Up to like & getrecommendations! Published in 2017 at "Cancer"
DOI: 10.1002/cncr.31055
Abstract: The adequate histologic subtyping of non–small cell lung cancer (NSCLC) secondary to the clinical need of tailoring systemic therapies has been challenged by small sample sizes of primary or metastatic lung tumors obtained through fineneedle… read more here.
Keywords: medicine; precision medicine; biomarker; disease ... See more keywords
Comprehensive epithelial biomarker analysis of malignant mesothelioma: EpCAM positivity is a potential diagnostic pitfall.
Sign Up to like & getrecommendations! Published in 2023 at "Cancer cytopathology"
DOI: 10.1002/cncy.22706
Abstract: BACKGROUND Epithelial cell adhesion molecule (EpCAM) is frequently used to distinguish carcinoma from background mesothelial cells during cytologic examination of body cavity fluids. Previously, the authors identified one malignant mesothelioma case with strong and diffuse… read more here.
Keywords: epcam; epcam positivity; malignant mesothelioma; biomarker ... See more keywords