Long noncoding RNAs biomarker‐based cancer assessment
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Cellular Physiology"
DOI: 10.1002/jcp.28417
Abstract: Cancer diagnosis have mainly relied on the incorporation of molecular biomarkers as part of routine diagnostic tool. The molecular alteration ranges from those involving DNA, RNA, noncoding RNAs (microRNAs and long noncoding RNAs [lncRNAs]) and… read more here.
Keywords: long noncoding; biomarker based; noncoding rnas; cancer ... See more keywords
Biomarker-based Bayesian randomized clinical trial design for identifying a target population.
Sign Up to like & getrecommendations! Published in 2023 at "Statistics in medicine"
DOI: 10.1002/sim.9749
Abstract: The challenges and potential benefits of incorporating biomarkers into clinical trial designs have been increasingly discussed, in particular to develop new agents for immune-oncology or targeted cancer therapies. To more accurately identify a sensitive subpopulation… read more here.
Keywords: oncology; biomarker based; trial; design ... See more keywords
Confounders for interpreting the benefit of a biomarker-based strategy in early discontinuation of empirical antifungal therapy
Sign Up to like & getrecommendations! Published in 2018 at "Intensive Care Medicine"
DOI: 10.1007/s00134-018-5068-1
Abstract: Initial correspondence from Drs. Yamaga, Ohshimo and Shime We would like to discuss factors that potentially affect the results of a biomarker-based antifungal therapeutic algorithm in a recent issue of Intensive Care Medicine [1]. First,… read more here.
Keywords: medicine; antifungal therapy; confounders interpreting; biomarker based ... See more keywords
Biomarker-based evaluation of cytogenotoxic potential of glyphosate in Vigna mungo (L.) Hepper genotypes
Sign Up to like & getrecommendations! Published in 2021 at "Environmental Monitoring and Assessment"
DOI: 10.1007/s10661-021-08865-x
Abstract: Herbicides have proven to be a boon for agricultural fields. Their inherent property to kill weeds and unwanted vegetation makes them an essential biological tool for farmers and agricultural systems. Besides being capable of destroying… read more here.
Keywords: vigna mungo; glyphosate vigna; glyphosate; biomarker based ... See more keywords
An Appraisal of Biomarker-Based Risk-Scoring Models in Chronic Heart Failure: Which One Is Best?
Sign Up to like & getrecommendations! Published in 2018 at "Current Heart Failure Reports"
DOI: 10.1007/s11897-018-0375-y
Abstract: Purpose of ReviewWhile prediction models incorporating biomarkers are used in heart failure, these have shown wide-ranging discrimination and calibration. This review will discuss externally validated biomarker-based risk models in chronic heart failure patients assessing their… read more here.
Keywords: chronic heart; heart; biomarker based; heart failure ... See more keywords
Biomarker-Based Visceral Adiposity Score and Incident Type 2 Diabetes in the Multiethnic Cohort.
Sign Up to like & getrecommendations! Published in 2021 at "Annals of epidemiology"
DOI: 10.1016/j.annepidem.2021.07.002
Abstract: PURPOSE Visceral adipose tissue (VAT) may be more important than subcutaneous fat in type 2 diabetes (T2D) etiology. We examined a VAT score developed in reference to MRI measurement of VAT in the Multiethnic Cohort… read more here.
Keywords: incident; multiethnic cohort; biomarker based; type diabetes ... See more keywords
Biomarker-based assessment of the toxicity of the antifungal clotrimazol to the microcrustacean Daphnia magna.
Sign Up to like & getrecommendations! Published in 2019 at "Environmental toxicology and pharmacology"
DOI: 10.1016/j.etap.2019.103210
Abstract: Among the vast list of xenobiotics that may promote harmful effects in aquatic ecosystems, pharmaceuticals are currently a prominent class due to their ability to persist in these environments and also due to the lack… read more here.
Keywords: toxicity; biomarker based; daphnia magna; toxicity antifungal ... See more keywords
Mass-production and biomarker-based characterization of high-value Spirulina powder for nutritional supplements.
Sign Up to like & getrecommendations! Published in 2020 at "Food chemistry"
DOI: 10.1016/j.foodchem.2020.126751
Abstract: Mass-produced Spirulina powder was characterized based on biomarkers for quality assessment. Other Spirulina powder products for functional foods and animal feeds were used as controls. In this study, Spirulina platensis was mass-cultured in modified Spirulina… read more here.
Keywords: spirulina powder; mass; biomarker based; mass produced ... See more keywords
The path to biomarker-based diagnostic criteria for the spectrum of neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2020 at "Expert Review of Molecular Diagnostics"
DOI: 10.1080/14737159.2020.1731306
Abstract: ABSTRACT Introduction: The postmortem examination still represents the reference standard for detecting the pathological nature of chronic neurodegenerative diseases (NDD). This approach displays intrinsic conceptual limitations since NDD represent a dynamic spectrum of partially overlapping… read more here.
Keywords: biomarker based; neurodegenerative diseases; based diagnostic; diagnostic criteria ... See more keywords
Toward more informative biomarker-based clinical trials in glioblastoma.
Sign Up to like & getrecommendations! Published in 2017 at "Neuro-oncology"
DOI: 10.1093/neuonc/nox063
Abstract: Given the significant advances using both targeted therapies and immunotherapies in other solid tumors, the therapeutic advances in glioblastoma (GBM) are particularly disappointing. One might think that an important factor is a lack of understanding… read more here.
Keywords: toward informative; trial; biomarker subtypes; biomarker ... See more keywords
An in Silico, Biomarker-Based Method for the Evaluation of Virtual Neuropsychiatric Drug Effects
Sign Up to like & getrecommendations! Published in 2017 at "Neural Computation"
DOI: 10.1162/neco_a_00944
Abstract: The recent explosion in neuroscience research has markedly increased our understanding of the neurobiological correlates of many psychiatric illnesses, but this has unfortunately not translated into more effective pharmacologic treatments for these conditions. At the… read more here.
Keywords: methodology; biomarker based; drug; based method ... See more keywords