A cross‐sectional study of the FDA approved indications and supporting pivotal trials of small‐molecular kinase inhibitors in cancer therapies with the biomarker of cancer driver gene
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DOI: 10.1002/ijc.34222
Abstract: Cancer precision medicine with biomarker of cancer driver gene (CDG) has been achieved by many small‐molecular kinase inhibitors (SMKIs) approved by the US Food and Drug Administration (FDA). Publicly available FDA documents were collected for… read more here.
Keywords: driver gene; biomarker; small molecular; biomarker cancer ... See more keywords
Detecting the Sweet Biomarker on Cancer Cells
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DOI: 10.1021/acscentsci.8b00156
Abstract: A sugar molecule expressed on cancer cells can be chemoenzymatically labeled for fluorescent imaging and proteomic analysis. read more here.
Keywords: detecting sweet; cancer cells; sweet biomarker; biomarker cancer ... See more keywords
The potential of circulating cell free RNA as a biomarker in cancer
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DOI: 10.1080/14737159.2019.1633307
Abstract: ABSTRACT Introduction: It is now clear that circulating cell-free ribonucleic acids (ccfRNAs), including messenger RNA (mRNA) and miRNA, are potential cancer biomarkers. As ccfmiRNA is relatively more stable than ccfmRNA, research should concentrate on developing… read more here.
Keywords: rna; cell free; circulating cell; biomarker cancer ... See more keywords
LINC00520: A Potential Diagnostic and Prognostic Biomarker in Cancer
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DOI: 10.3389/fimmu.2022.845418
Abstract: Long non-coding RNA (lncRNA) is important in the study of cancer mechanisms. LINC00520 is located on human chromosome 14q22.3 and is a highly conserved long non-coding RNA. LINC00520 is widely expressed in various tissues. The… read more here.
Keywords: cancer; expression linc00520; linc00520 potential; biomarker cancer ... See more keywords
PTEN as a Prognostic/Predictive Biomarker in Cancer: An Unfulfilled Promise?
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DOI: 10.3390/cancers11040435
Abstract: Identifying putative biomarkers of clinical outcomes in cancer is crucial for successful enrichment, and for the selection of patients who are the most likely to benefit from a specific therapeutic approach. Indeed, current research in… read more here.
Keywords: predictive biomarker; prognostic predictive; biomarker cancer; cancer ... See more keywords