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Published in 2017 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2016.02.035
Abstract: Biomarkers can be regarded as highly objective, quantifiable, and reproducible medical signs, that is, “objective indications of medical state observed from outside the patientdin contrast to medical symptoms, which are perceived by patients themselves” (Strimbu…
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Keywords:
biomarker research;
alzheimer disease;
biomarker;
disease ... See more keywords
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Published in 2023 at "Genetic testing and molecular biomarkers"
DOI: 10.1089/gtmb.2022.0086
Abstract: A frequent topic of biomedical research is the potential clinical use of non-coding (nc) RNAs as quantitative biomarkers for a broad spectrum of health and disease. However, ncRNA analyses have not been pressed into widespread…
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Keywords:
biomarker;
biomarker development;
analytic quality;
quality system ... See more keywords
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Published in 2017 at "Cancer Research"
DOI: 10.1158/1538-7445.am2017-4815
Abstract: The field of cancer immunology is rapidly moving towards innovative therapeutic strategies. As a consequence the need for robust and predictive preclinical platforms arises just as well. The current project aims to establish a drug…
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Keywords:
treatment;
single mouse;
drug screening;
biomarker development ... See more keywords
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Published in 2020 at "Neurology"
DOI: 10.1212/wnl.0000000000009107
Abstract: A fundamental question in advancing Parkinson disease (PD) research is whether it represents one disorder or many. Does each genetic PD inform a common pathobiology or represent a unique entity? Do the similarities between genetic…
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Keywords:
biomarker development;
modification biomarker;
disease modification;
parkinson disease ... See more keywords
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Published in 2022 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2022.890638
Abstract: Proteomics studies have shown differential expression of numerous proteins in dementias but have rarely led to novel biomarker tests for clinical use. The Marie Curie MIRIADE project is designed to experimentally evaluate development strategies to…
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Keywords:
miriade;
multi omics;
biomarker;
biomarker development ... See more keywords