Cellwise outlier detection and biomarker identification in metabolomics based on pairwise log ratios
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Chemometrics"
DOI: 10.1002/cem.3182
Abstract: Data outliers can carry very valuable information and might be most informative for the interpretation. Nevertheless, they are often neglected. An algorithm called cellwise outlier diagnostics using robust pairwise log ratios (cell‐rPLR) for the identification… read more here.
Keywords: pairwise log; log ratios; biomarker identification; cellwise outlier ... See more keywords
Cognitive Phenotypes for Biomarker Identification in Mental Illness: Forward and Reverse Translation.
Sign Up to like & getrecommendations! Published in 2018 at "Current topics in behavioral neurosciences"
DOI: 10.1007/7854_2018_50
Abstract: Psychiatric illness has been acknowledged for as long as people were able to describe behavioral abnormalities in the general population. In modern times, these descriptions have been codified and continuously updated into manuals by which… read more here.
Keywords: illness; biomarker identification; identification mental; cognitive phenotypes ... See more keywords
Plasma Biomarker Identification and Quantification by Microparticle Proteomics.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7057-5_33
Abstract: Plasma biomarker discovery necessitates a method for deep proteomic profiling, as well as for highly accurate quantification of the proteins in the sample. Furthermore, to obtain strong candidates for potential biomarkers, the method should be… read more here.
Keywords: identification quantification; quantification; biomarker identification; plasma biomarker ... See more keywords
Metabolomics in renal cell carcinoma: From biomarker identification to pathomechanism insights.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108623
Abstract: Renal cell carcinoma (RCC) is a frequently diagnosed cancer with high prevalence, which is inversely associated with survival benefit. Although myriad studies have shed light on disease causality, unfortunately, thus far, RCC diagnosis is faced… read more here.
Keywords: cell carcinoma; renal cell; biomarker identification;
Tumor genomic analysis for biomarker identification in a phase I trial of the Wee 1 inhibitor adavosertib (AZD1775).
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2020.38.15_suppl.3624
Abstract: 3624Background: Adavosertib, a first-in-class Wee1 kinase inhibitor, abrogates G2/M cell cycle arrest causing premature mitosis and DNA replication stress, yielding enhanced DNA damage. Here we rep... read more here.
Keywords: inhibitor; analysis biomarker; identification phase; biomarker identification ... See more keywords