Biomarker signature and pathophysiological pathways in patients with chronic heart failure and metabolic syndrome
Sign Up to like & getrecommendations! Published in 2023 at "European Journal of Heart Failure"
DOI: 10.1002/ejhf.2760
Abstract: The comorbidities that collectively define metabolic syndrome are common in patients with heart failure. However, the role of metabolic syndrome in the pathophysiology of heart failure is not well understood. We therefore investigated the clinical… read more here.
Keywords: biomarker signature; metabolic syndrome; heart failure; heart ... See more keywords
Cognitive Impairment and Diminished Neural Responses Constitute a Biomarker Signature of Negative Symptoms in Psychosis.
Sign Up to like & getrecommendations! Published in 2020 at "Schizophrenia bulletin"
DOI: 10.1093/schbul/sbaa001
Abstract: The treatment of negative symptoms (NS) in psychosis represents an urgent unmet medical need given the significant functional impairment it contributes to psychosis syndromes. The lack of progress in treating NS is impacted by the… read more here.
Keywords: biomarker signature; negative symptoms; biomarker; symptoms psychosis ... See more keywords
Definition of an Inflammatory Biomarker Signature in Plasma-Derived Extracellular Vesicles of Glioblastoma Patients
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10010125
Abstract: Glioblastoma (GB) is an aggressive type of tumour for which therapeutic options and biomarkers are limited. GB diagnosis mostly relies on symptomatic presentation of the tumour and, in turn, brain imaging and invasive biopsy that… read more here.
Keywords: biomarker signature; extracellular vesicles; diagnosis; plasma ... See more keywords
Obtaining Reliable RT-qPCR Results in Molecular DiagnosticsâMIQE Goals and Pitfalls for Transcriptional Biomarker Discovery
Sign Up to like & getrecommendations! Published in 2022 at "Life"
DOI: 10.3390/life12030386
Abstract: In this review, we discuss the development pipeline for transcriptional biomarkers in molecular diagnostics and stress the importance of a reliable gene transcript quantification strategy. Hence, a further focus is put on the MIQE guidelines… read more here.
Keywords: biomarker signature; biomarker; transcriptional biomarker; biomarker discovery ... See more keywords