Pattern mixture models for clinical validation of biomarkers in the presence of missing data.
Sign Up to like & getrecommendations! Published in 2017 at "Statistics in medicine"
DOI: 10.1002/sim.7328
Abstract: Targeted therapies for cancers are sometimes only effective in a subset of patients with a particular biomarker status. In clinical development, the biomarker status is typically determined by an investigational-use-only/laboratory-developed test. A market ready test… read more here.
Keywords: biomarker status; biomarker; pattern mixture; clinical validation ... See more keywords
B-Vitamin Intake and Biomarker Status in Relation to Cognitive Decline in Healthy Older Adults in a 4-Year Follow-Up Study
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DOI: 10.3390/nu9010053
Abstract: Advancing age can be associated with an increase in cognitive dysfunction, a spectrum of disability that ranges in severity from mild cognitive impairment to dementia. Folate and the other B-vitamins involved in one-carbon metabolism are… read more here.
Keywords: decline; biomarker status; year; cognitive decline ... See more keywords