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Published in 2017 at "Movement Disorders"
DOI: 10.1002/mds.27090
Abstract: Parkinson's disease biomarkers are needed to increase diagnostic accuracy, to objectively monitor disease progression and to assess therapeutic efficacy as well as target engagement when evaluating novel drug and therapeutic strategies. This article summarizes perianalytical…
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Keywords:
synuclein;
perianalytical considerations;
biomarker studies;
biomarker ... See more keywords
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Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-05542-4_11
Abstract: Autism spectrum disorder (ASD) is a neurological and developmental condition that begins early in childhood and lasts throughout life. The epidemiology of ASD is continuously increasing all over the world with huge social and economical…
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Keywords:
spectrum disorders;
studies autism;
epidemiology;
biomarker studies ... See more keywords
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Published in 2022 at "Biomarkers"
DOI: 10.1080/1354750x.2022.2093399
Abstract: Abstract Diagnostic statistics such as sensitivity and specificity are widely used in the assessment of biomarkers. Interpretation of these and other statistics derived from a 2 × 2 table can be complex. The properties of the commonly…
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Keywords:
biomarker studies;
statistical analysis;
studies four;
commentary statistical ... See more keywords
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Published in 2020 at "Neurology"
DOI: 10.1212/wnl.0000000000010714
Abstract: A major advance in Alzheimer disease (AD) research over the past decade has been the development of PET and CSF biomarkers for amyloid and tau. They are now part of the most recent National Institute…
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Keywords:
biomarker studies;
disease biomarker;
alzheimer disease;
extending alzheimer ... See more keywords
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Published in 2018 at "Frontiers in Public Health"
DOI: 10.3389/fpubh.2018.00181
Abstract: Dementia can result from a number of distinct diseases with differing etiology and pathophysiology. Even within the same disease, there is considerable phenotypic heterogeneity with varying symptoms and disease trajectories. Dementia diagnosis is thus very…
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Keywords:
phenotypic heterogeneity;
dementia;
biomarker;
disease ... See more keywords