Articles with "biomarkers clinical" as a keyword



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Brainstem Biomarkers of Clinical Variant and Pathology in Progressive Supranuclear Palsy

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Published in 2021 at "Movement Disorders"

DOI: 10.1002/mds.28901

Abstract: Magnetic resonance brainstem measurements are useful structural biomarkers in the Richardson's syndrome variant of progressive supranuclear palsy (PSP). However, it is unclear how these biomarkers differ across the phenotypic spectrum of PSP and how they… read more here.

Keywords: biomarkers clinical; pathology; progressive supranuclear; supranuclear palsy ... See more keywords

Effect of aging on biomarkers and clinical profile in Parkinson’s disease

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Published in 2025 at "Journal of Neurology"

DOI: 10.1007/s00415-025-13384-7

Abstract: Parkinson’s disease (PD) has different progression rates and disease characteristics according to age of onset, the younger being less cognitively affected and experiencing more motor fluctuations. We explored different pathophysiologic mechanisms underlying PD in patients… read more here.

Keywords: disease; aging biomarkers; clinical profile; biomarkers clinical ... See more keywords

Biomarkers and Clinical Laboratory Detection of Acute and Chronic Ethanol Use.

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Published in 2022 at "Clinical chemistry"

DOI: 10.1093/clinchem/hvac004

Abstract: BACKGROUND Ethanol use can lead to many health and socio-economic problems. Early identification of risky drinking behaviors helps provide timely clinical and social interventions. Laboratory testing of biomarkers of ethanol use supports the timely identification… read more here.

Keywords: acute; ethanol; utility; biomarkers clinical ... See more keywords

Effects of diabetes/hyperglycemia on peri-implant biomarkers and clinical and radiographic outcomes in patients with dental implant restorations: A systematic review and meta-analysis.

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Published in 2022 at "Clinical oral implants research"

DOI: 10.1111/clr.14010

Abstract: OBJECTIVE To systematically analyze the effects of diabetes mellitus/hyperglycemia (DM/HG) on peri-implant biomarkers and clinical and radiographic outcomes in patients undergoing implant treatment. MATERIALS AND METHODS PubMed, Embase, and the Cochrane Central Register of Controlled… read more here.

Keywords: implant biomarkers; peri implant; analysis; biomarkers clinical ... See more keywords

Circulating Oxidative Stress Biomarkers in Clinical Studies on Type 2 Diabetes and Its Complications

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Published in 2019 at "Oxidative Medicine and Cellular Longevity"

DOI: 10.1155/2019/5953685

Abstract: Type 2 diabetes (T2DM) and its complications constitute a major worldwide public health problem, with high rates of morbidity and mortality. Biomarkers for predicting the occurrence and development of the disease may therefore offer benefits… read more here.

Keywords: type diabetes; stress; damage; stress biomarkers ... See more keywords

Abstract 4616: Detection of phosphorylated biomarkers in clinical blood samples: a flow cytometry platform utilizing smart tube fixation

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Published in 2025 at "Cancer Research"

DOI: 10.1158/1538-7445.am2025-4616

Abstract: The identification and quantification of biomarkers in clinical blood samples play a pivotal role in personalized medicine, enabling disease monitoring and therapeutic assessment. Protein phosphorylation, a key post-translational modification, reflects cellular signaling in immune or… read more here.

Keywords: clinical blood; biomarkers clinical; flow cytometry; blood ... See more keywords

Cardiac MRI in diabetic cardiomyopathy: translating imaging biomarkers into clinical practice.

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Published in 2025 at "Cardiovascular diabetology"

DOI: 10.1186/s12933-025-03019-6

Abstract: Diabetic cardiomyopathy (DbCM) is a progressive cardiac disorder characterized by left ventricular dysfunction in the presence of diabetes mellitus. With the rising global prevalence of diabetes, early detection and intervention are crucial to prevent transition… read more here.

Keywords: biomarkers clinical; clinical practice; imaging biomarkers; diabetic cardiomyopathy ... See more keywords
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Combination of transcriptional biomarkers and clinical parameters for early prediction of sepsis indued acute respiratory distress syndrome

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Published in 2023 at "Frontiers in Immunology"

DOI: 10.3389/fimmu.2022.1084568

Abstract: Objective As a common yet intractable complication of severe sepsis, acute respiratory distress syndrome (ARDS) is closely associated with poor clinical outcomes and elevated medical expenses. The aim of the current study is to generate… read more here.

Keywords: transcriptional biomarkers; acute respiratory; clinical parameters; prediction ... See more keywords
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Current Landscape of NRF2 Biomarkers in Clinical Trials

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Published in 2020 at "Antioxidants"

DOI: 10.3390/antiox9080716

Abstract: The transcription factor NF-E2 p45-related factor 2 (NRF2; encoded by NFE2L2) plays a critical role in the maintenance of cellular redox and metabolic homeostasis, as well as the regulation of inflammation and cellular detoxication pathways.… read more here.

Keywords: landscape nrf2; nrf2; clinical trials; current landscape ... See more keywords

Liquid Biopsy-Derived Tumor Biomarkers for Clinical Applications in Glioblastoma

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Published in 2025 at "Biomolecules"

DOI: 10.3390/biom15050658

Abstract: Glioblastoma (GBM) is the most aggressive primary brain tumor in adults, characterized by rapid growth and resistance to chemotherapy. Conventional treatments remain largely ineffective, with patient survival averaging around 18 months after diagnosis. Current diagnostic… read more here.

Keywords: liquid biopsy; biomarkers clinical; biopsy; derived tumor ... See more keywords

Genetic Biomarkers and Their Clinical Implications in B-Cell Acute Lymphoblastic Leukemia in Children

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Published in 2022 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms23052755

Abstract: Acute lymphoblastic leukemia (ALL) is a heterogeneous group of hematologic malignancies characterized by abnormal proliferation of immature lymphoid cells. It is the most commonly diagnosed childhood cancer with an almost 80% cure rate. Despite favorable… read more here.

Keywords: clinical implications; genetic biomarkers; lymphoblastic leukemia; acute lymphoblastic ... See more keywords