Integration of bioinformatics analysis and experimental validation identifies plasma exosomal miR‐103b/877‐5p/29c‐5p as diagnostic biomarkers for early lung adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Cancer Medicine"
DOI: 10.1002/cam4.4788
Abstract: The aim of this study was to identify miRNAs in plasma exosomes as noninvasive biomarkers for the early diagnosis of lung adenocarcinoma (LUAD). First, exosomal miRNA profiling of three patients with early LUAD and three… read more here.
Keywords: biomarkers early; hsa mir; 103b 877; mir 103b ... See more keywords
Potential plasma lipid biomarkers in early-stage breast cancer
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DOI: 10.1007/s10529-017-2417-z
Abstract: ObjectiveTo find new biomarkers for early diagnosis of breast cancer.Results847 lipid species were identified from 78 plasma samples (37 breast cancer samples and 41 healthy controls) by ultra HPLC coupled with quadrupole time-of-flight tandem mass… read more here.
Keywords: cancer; biomarkers early; potential plasma; breast cancer ... See more keywords
Genome-Wide Identification of Drought Response Genes in Soybean Seedlings and Development of Biomarkers for Early Diagnoses
Sign Up to like & getrecommendations! Published in 2018 at "Plant Molecular Biology Reporter"
DOI: 10.1007/s11105-018-1085-z
Abstract: Drought is a yield-limiting factor for soybean (Glycine max L. Merrill) production in North America. Understanding molecular mechanisms underlying early responses of the soybean plant to drought may help develop new techniques to manage the… read more here.
Keywords: genome wide; wide identification; biomarkers early; plant ... See more keywords
Potential biomarkers for early detection of diabetic kidney disease.
Sign Up to like & getrecommendations! Published in 2020 at "Diabetes research and clinical practice"
DOI: 10.1016/j.diabres.2020.108082
Abstract: INTRODUCTION To assess the potential of galectin-3 and growth differentiation factor-15 (GDF-15) biomarkers for the early detection of diabetic kidney disease (DKD). METHODOLOGY This was a cross-sectional study conducted over a period of 1.2 years.… read more here.
Keywords: detection diabetic; biomarkers early; early detection; gdf ... See more keywords
PIWI-interacting RNA sequencing profiles in maternal plasma-derived exosomes reveal novel non-invasive prenatal biomarkers for the early diagnosis of nonsyndromic cleft lip and palate
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DOI: 10.1016/j.ebiom.2021.103253
Abstract: Background Congenital malformations are common birth defects with high neonatal morbidity and mortality. It is essential to find simpler and more efficient biomarkers for early prenatal diagnosis. Therefore, we investigated PIWI-interacting RNAs (piRNAs) as potential… read more here.
Keywords: piwi interacting; biomarkers early; women carrying; normal foetuses ... See more keywords
Novel non-protein biomarkers for early detection of hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2021 at "Engineering"
DOI: 10.1016/j.eng.2021.02.020
Abstract: Abstract Early detection of hepatocellular carcinoma (HCC) while in its early stages is critical for reducing HCC mortality in high-risk patients. However, highly sensitive and specific surveillance biomarkers for early-stage HCC detection are still lacking.… read more here.
Keywords: hepatocellular carcinoma; detection hepatocellular; early detection; biomarkers early ... See more keywords
IDENTIFICATION AND ASSESSMENT OF CANDIDATE BIOMARKERS IN EARLY DETECTION AND PROGRESSION OF ORAL SQUAMOUS CELL CARCINOMA
Sign Up to like & getrecommendations! Published in 2021 at "Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology"
DOI: 10.1016/j.oooo.2021.03.141
Abstract: Background An integrated approach for understanding molecular transformation of OSCC, facilitating early detection of invasion and metastasis is sustainable. The workflow, including bioinformatics to predict candidate genes, confirming their presence with proteomics and validation of… read more here.
Keywords: candidate; progression; candidate biomarkers; early detection ... See more keywords
Elevated plasma miR-133b and miR-221-3p as biomarkers for early Parkinson’s disease
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DOI: 10.1038/s41598-021-94734-z
Abstract: Blood circulating microRNAs (miRNAs) are proposed to be promising biomarkers for many neurodegenerative disorders, including Parkinson’s disease (PD). However, there is a lack of identified differentially expressed miRNAs in PD from different studies. The aim… read more here.
Keywords: mir 133b; biomarkers early; 133b mir; mir ... See more keywords
Putative biomarkers for early detection of mastitis in cattle
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DOI: 10.1071/an19539
Abstract: Context Mastitis is an inflammation of mammary gland parenchyma, and is an unending cause of economic loss to the dairy industry. The interest in research on biomarker discovery for the diagnosis of bovine mastitis stems… read more here.
Keywords: biomarkers early; mastitis; early detection; analysis ... See more keywords
The role of urine and serum biomarkers in the early detection of ovarian epithelial tumours
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Obstetrics and Gynaecology"
DOI: 10.1080/01443615.2022.2151352
Abstract: Abstract Ovarian cancer (OC) is one of the leading causes of gynaecological cancer mortality in women worldwide. If detected at an early stage (I, II), OC has a 90% 5-year survival rate; nevertheless, symptoms are… read more here.
Keywords: biomarkers early; serum biomarkers; role; early detection ... See more keywords
Abstract P5-07-09: Identification of miRNA biomarkers for early diagnosis of basal-like breast cancer
Sign Up to like & getrecommendations! Published in 2018 at "Cancer Research"
DOI: 10.1158/1538-7445.sabcs17-p5-07-09
Abstract: The routine screening for breast cancer relies primarily on imaging techniques such as mammography and ultrasonography, but it is often not sensitive enough for early detection and requires complementary approaches. Recent studies suggest that microRNAs… read more here.
Keywords: biomarkers early; like breast; breast cancer; cancer ... See more keywords