Association of longitudinal white matter degeneration and cerebrospinal fluid biomarkers of neurodegeneration, inflammation and Alzheimer’s disease in late-middle-aged adults
Sign Up to like & getrecommendations! Published in 2017 at "Brain Imaging and Behavior"
DOI: 10.1007/s11682-017-9732-9
Abstract: Alzheimer’s disease (AD) is characterized by substantial neurodegeneration, including both cortical atrophy and loss of underlying white matter fiber tracts. Understanding longitudinal alterations to white matter may provide new insights into trajectories of brain change… read more here.
Keywords: matter; inflammation; late middle; biomarkers neurodegeneration ... See more keywords
Axonal transport proteins as biomarkers of neurodegeneration?
Sign Up to like & getrecommendations! Published in 2017 at "Biomarkers in medicine"
DOI: 10.2217/bmm-2017-0163
Abstract: Neurodegeneration is a cardinal feature of numerous neurological diseases, yet the mechanisms underlying neurodegeneration are disparate and are not currently fully understood. In addition, the diagnosis of neurodegenerative conditions is often challenging and treatments are… read more here.
Keywords: biomarkers neurodegeneration; transport proteins; axonal transport; proteins biomarkers ... See more keywords
Biomarkers of Neurodegeneration in Autoimmune-Mediated Encephalitis
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2018.00668
Abstract: Progranulin (PGRN), Total-Tau (t-tau), and Neurofilament light chain (NfL) are well known biomarkers of neurodegeneration. The objective of the present study was to investigate whether these parameters represent also biomarkers in autoimmune-mediated Encephalitis (AE) and… read more here.
Keywords: csf patients; tau; mediated encephalitis; autoimmune mediated ... See more keywords
Insights Into the Proteomic Profiling of Extracellular Vesicles for the Identification of Early Biomarkers of Neurodegeneration
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Neurology"
DOI: 10.3389/fneur.2020.580030
Abstract: Extracellular vesicles (EVs) are involved in the development and progression of neurodegenerative diseases, including Alzheimer's and Parkinson's disease. Moreover, EVs have the capacity to modify the physiology of neuronal circuits by transferring proteins, RNA, lipids,… read more here.
Keywords: extracellular vesicles; insights proteomic; neurodegenerative diseases; proteomic profiling ... See more keywords
Serum-Based Biomarkers in Neurodegeneration and Multiple Sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10051077
Abstract: Multiple Sclerosis (MS) is a debilitating disease with typical onset between 20 and 40 years of age, so the disability associated with this disease, unfortunately, occurs in the prime of life. At a very early… read more here.
Keywords: serum based; disease; biomarkers neurodegeneration; based biomarkers ... See more keywords
Imaging Biomarkers in Neurodegeneration
Sign Up to like & getrecommendations! Published in 2021 at "Biomarkers"
DOI: 10.36648/2472-1646.21.7.96
Abstract: Biomarkers in the arrangement and finding of neurodegenerative problems. The utilization of imaging biomarkers explicitly for the in vivo examination of neurodegenerative issues has expanded considerably over the previous many years and keeps on giving… read more here.
Keywords: imaging biomarkers; biomarkers neurodegeneration;
The metabolome identity: basis for discovery of biomarkers in neurodegeneration
Sign Up to like & getrecommendations! Published in 2019 at "Neural Regeneration Research"
DOI: 10.4103/1673-5374.245464
Abstract: Neurodegenerative disorders are often associated with cellular dysfunction caused by underlying protein-misfolding signalling. Numerous neuropathologies are diagnosed at late stage symptomatic changes which occur in response to these molecular malfunctions and treatment is often too… read more here.
Keywords: discovery biomarkers; basis discovery; identity basis; disease ... See more keywords
Prognostic value of complementary biomarkers of neurodegeneration in a mixed memory clinic cohort
Sign Up to like & getrecommendations! Published in 2020 at "PeerJ"
DOI: 10.7717/peerj.9498
Abstract: Background Biomarkers of neurodegeneration, e.g. MRI brain atrophy and [18F]FDG-PET hypometabolism, are often evaluated in patients suspected of neurodegenerative disease. Objective Our primary objective was to investigate prognostic properties of atrophy and hypometabolism. Methods From… read more here.
Keywords: memory clinic; hypometabolism; value; biomarkers neurodegeneration ... See more keywords