Plasma biomarkers for neurodegenerative disorders: ready for prime time?
Sign Up to like & getrecommendations! Published in 2023 at "Current Opinion in Psychiatry"
DOI: 10.1097/yco.0000000000000851
Abstract: Purpose of review Several plasma biomarkers for Alzheimer's disease and related disorders (ADRD) have demonstrated clinical and technical robustness. However, are they ready for clinical implementation? This review critically appraises current evidence for and against… read more here.
Keywords: plasma biomarkers; time; biomarkers neurodegenerative; plasma ... See more keywords
Blood Biomarkers in Neurodegenerative Diseases: Implications for the Clinical Neurologist.
Sign Up to like & getrecommendations! Published in 2023 at "Neurology"
DOI: 10.1212/wnl.0000000000207193
Abstract: Blood-based biomarkers offer a major advance in the clinical evaluation of neurodegenerative diseases. Currently, research studies have reported robust assays of blood markers for the detection of amyloid and tau pathologies specific to Alzheimer's disease… read more here.
Keywords: biomarkers neurodegenerative; diseases implications; blood biomarkers; implications clinical ... See more keywords
Biomarkers of Neurodegenerative Diseases: Biology, Taxonomy, Clinical Relevance, and Current Research Status
Sign Up to like & getrecommendations! Published in 2022 at "Biomedicines"
DOI: 10.3390/biomedicines10071760
Abstract: The understanding of neurodegenerative diseases, traditionally considered to be well-defined entities with distinguishable clinical phenotypes, has undergone a major shift over the last 20 years. The diagnosis of neurodegenerative diseases primarily requires functional brain imaging… read more here.
Keywords: biology taxonomy; biomarkers neurodegenerative; research; diseases biology ... See more keywords
Analysis of the Biomarkers for Neurodegenerative Diseases in Aged Progranulin Deficient Mice
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23020629
Abstract: Neurodegenerative diseases are debilitating impairments that affect millions of people worldwide and are characterized by progressive degeneration of structure and function of the central or peripheral nervous system. Effective biomarkers for neurodegenerative diseases can be… read more here.
Keywords: mice; biomarkers neurodegenerative; deficient mice; pgrn ... See more keywords
Biomarkers in Neurodegenerative Diseases: Proteomics Spotlight on ALS and Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23169299
Abstract: Neurodegenerative diseases such as amyotrophic lateral sclerosis (ALS) and Parkinson’s disease (PD) are both characterized by pathogenic protein aggregates that correlate with the progressive degeneration of neurons and the loss of behavioral functions. Both diseases… read more here.
Keywords: als parkinson; biomarkers neurodegenerative; disease; parkinson disease ... See more keywords
Autoantibodies targeting neuronal proteins as biomarkers for neurodegenerative diseases
Sign Up to like & getrecommendations! Published in 2022 at "Theranostics"
DOI: 10.7150/thno.72126
Abstract: Neurodegenerative diseases (NDDs) are associated with the accumulation of a range of misfolded proteins across the central nervous system and related autoimmune responses, including the generation of antibodies and the activation of immune cells. Both… read more here.
Keywords: biomarkers neurodegenerative; autoantibodies targeting; proteins biomarkers; neuronal proteins ... See more keywords