Biofluid Biomarkers in Parkinson's Disease: Clarity Amid Controversy
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DOI: 10.1002/mds.28030
Abstract: A critical need exists to develop biomarkers for Parkinson’s disease (PD). Facilitating the evolution toward personalized medicine, validated biomarkers hold the promise of improved diagnostic accuracy, disease monitoring, patient stratification, and objectively measuring treatment responses.… read more here.
Keywords: disease clarity; biomarkers parkinson; disease; biofluid biomarkers ... See more keywords
Sleep disorder and altered locomotor activity as biomarkers of the Parkinson’s disease cholinopathy in rat
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2017.11.021
Abstract: HIGHLIGHTSHippocampal sleep disorder is the first and long‐lasting hallmark of PD cholinopathy.High voltage sleep spindle dynamics during REM sleep reflects PD cholinopathy.Hypokinesia reflects impaired cholinergic impact in motor control regulatory network.Amphetamine induces hyperactivity in the… read more here.
Keywords: biomarkers parkinson; disorder; sleep disorder; locomotor activity ... See more keywords
Recent Advances in Biomarkers for Parkinson’s Disease
Sign Up to like & getrecommendations! Published in 2018 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2018.00305
Abstract: Parkinson’s disease (PD) is one of the common progressive neurodegenerative disorders with several motor and non-motor symptoms. Most of the motor symptoms may appear at a late stage where most of the dopaminergic neurons have… read more here.
Keywords: biomarkers parkinson; advances biomarkers; motor; recent advances ... See more keywords
In search of Parkinson's disease biomarkers - is the answer in our mouths? A systematic review of the literature on salivary biomarkers of Parkinson's disease.
Sign Up to like & getrecommendations! Published in 2020 at "Neurologia i neurochirurgia polska"
DOI: 10.5603/pjnns.a2020.0011
Abstract: The identification of reliable biomarkers of Parkinson's disease (PD) is a pivotal step in the introduction of causal therapies. Saliva is a biofluid which may be involved in synuclein pathology in PD. We have reviewed… read more here.
Keywords: parkinson disease; literature; biomarkers parkinson; search parkinson ... See more keywords