Evaluating biomarkers for treatment selection from reproducibility studies.
Sign Up to like & getrecommendations! Published in 2020 at "Biostatistics"
DOI: 10.1093/biostatistics/kxaa019
Abstract: We consider evaluating new or more accurately measured predictive biomarkers for treatment selection based on a previous clinical trial involving standard biomarkers. Instead of rerunning the clinical trial with the new biomarkers, we propose a… read more here.
Keywords: treatment selection; treatment; reproducibility; standard biomarkers ... See more keywords
Biomarkers for treatment change and radiographic progression in patients with rheumatoid arthritis in remission: a 5 year follow-up study.
Sign Up to like & getrecommendations! Published in 2020 at "Rheumatology"
DOI: 10.1093/rheumatology/keaa258
Abstract: OBJECTIVE To identify biomarkers of treatment change and radiographic progression in patients with RA under remission. PATIENTS AND METHODS RA patients in remission (DAS28-ESR 10.47 (small detectable change). RESULTS Sixty patients were included, 81.6% were… read more here.
Keywords: change; year; remission; radiographic progression ... See more keywords
OA03 Harnessing quantitative proteomics to identify biomarkers of treatment response to etanercept in patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2023 at "Rheumatology"
DOI: 10.1093/rheumatology/kead104.003
Abstract: Tumour necrosis factor inhibitors (TNFi) are commonly prescribed to treat rheumatoid arthritis (RA), but response to TNFi is not universal and there are no validated pre-treatment biomarkers of treatment response at present. Proteins have many… read more here.
Keywords: biomarkers treatment; treatment response; treatment; none ... See more keywords
Immunotherapy and potential predictive biomarkers in the treatment of neuroendocrine neoplasia.
Sign Up to like & getrecommendations! Published in 2020 at "Future oncology"
DOI: 10.2217/fon-2020-0703
Abstract: Neuroendocrine neoplasias (NENs) are a heterogeneous group of rare tumors scattered throughout the body. Surgery, locoregional or ablative therapies as well as maintenance treatments are applied in well-differentiated, low-grade NENs, whereas cytotoxic chemotherapy is usually… read more here.
Keywords: potential predictive; immunotherapy potential; treatment; treatment neuroendocrine ... See more keywords