Microglial Membrane-Coated Biomimetic Nanoplatform for Enhanced Blood-Brain Barrier Penetration and Targeted Photodynamic Therapy in Orthotopic Glioblastoma.
Sign Up to like & getrecommendations! Published in 2025 at "Advanced healthcare materials"
DOI: 10.1002/adhm.202502808
Abstract: Glioblastoma multiforme (GBM) continues to pose a significant challenge in the field of neuro‐oncology primarily because of the limited penetration of therapeutics across the blood‐brain barrier (BBB) and the presence of immunosuppressive tumor microenvironments. To… read more here.
Keywords: biomimetic nanoplatform; blood brain; tumor; brain barrier ... See more keywords
Deep Penetrating and Sensitive Targeted Magnetic Particle Imaging and Photothermal Therapy of Early-Stage Glioblastoma Based on a Biomimetic Nanoplatform.
Sign Up to like & getrecommendations! Published in 2023 at "Advanced science"
DOI: 10.1002/advs.202300854
Abstract: Early diagnosis can effectively improve the survival of glioblastoma multiforme (GBM). A specific imaging technique that is simultaneously deep penetrating and sensitive to small tissue changes is desired to identify GBM. Due to its excellent… read more here.
Keywords: photothermal therapy; particle imaging; magnetic particle; penetrating sensitive ... See more keywords
All-In-One Biomimetic Nanoplatform Based on Hollow Polydopamine Nanoparticles for Synergistically Enhanced Radiotherapy of Colon Cancer.
Sign Up to like & getrecommendations! Published in 2022 at "Small"
DOI: 10.1002/smll.202107656
Abstract: Even though radiotherapy is the most important therapeutic strategy for colon cancer treatment, there is an enormous demand to improve radiosensitivity in solid tumor destruction. For this purpose, a biomimetic nanoplatform based on hollow polydopamine… read more here.
Keywords: hollow polydopamine; colon cancer; biomimetic nanoplatform; cancer ... See more keywords
A pH/Ultrasound dual-response biomimetic nanoplatform for nitric oxide gas-sonodynamic combined therapy and repeated ultrasound for relieving hypoxia.
Sign Up to like & getrecommendations! Published in 2019 at "Biomaterials"
DOI: 10.1016/j.biomaterials.2019.119636
Abstract: Sonodynamic therapy (SDT) has rapidly developed as a powerful alternative to traditional photodynamic therapy due to its intrinsically deeper tissue-penetration. However, single SDT dose is incapable of radical cure because the long-term hypoxia of tumor… read more here.
Keywords: hypoxia; gas; biomimetic nanoplatform; therapy ... See more keywords
An Intelligent Biomimetic Nanoplatform for Holistic Treatment of Metastatic Triple-Negative Breast Cancer via Photothermal Ablation and Immune Remodeling.
Sign Up to like & getrecommendations! Published in 2020 at "ACS nano"
DOI: 10.1021/acsnano.0c05392
Abstract: Metastasis is one of the main causes of failure in the treatment of triple-negative breast cancer (TNBC). Immunotherapy brings hope and opportunity to solve this challenge, while its clinical applications are greatly inhibited by the… read more here.
Keywords: immune remodeling; biomimetic nanoplatform; tnbc; intelligent biomimetic ... See more keywords
Peptide-Engineered Biomimetic Nanoplatform with Cell-Membrane Camouflage Streamlines High-Performance Isolation and Quantitation of Extracellular Vesicles.
Sign Up to like & getrecommendations! Published in 2025 at "ACS sensors"
DOI: 10.1021/acssensors.5c00827
Abstract: Reliable isolation and quantitation of extracellular vesicles (EVs), which function as natural bioactive nanocarriers in biological processes, are essential to uncovering their underlying mechanisms and applications. To meet these requirements, we present here a peptide-engineered… read more here.
Keywords: biomimetic nanoplatform; quantitation; cell; isolation ... See more keywords