Molecular Engineering of Pericellular Microniche via Biomimetic Proteoglycans Modulates Cell Mechanobiology.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c09015
Abstract: Molecular engineering of biological tissues using synthetic mimics of native matrix molecules can modulate the mechanical properties of the cellular microenvironment through physical interactions with existing matrix molecules, and in turn, mediate the corresponding cell… read more here.
Keywords: biomimetic proteoglycans; cell mechanobiology; molecular engineering;
Modulating physical properties of porcine urethra with injection of novel biomimetic proteoglycans ex vivo
Sign Up to like & getrecommendations! Published in 2019 at "Interface Focus"
DOI: 10.1098/rsfs.2019.0013
Abstract: Urinary incontinence is a significant challenge for women who are affected by it. We propose augmenting the tissue structure to restore normal biomechanics by molecularly engineering the tissue using a novel family of biomimetic proteoglycans… read more here.
Keywords: pbs; biomimetic proteoglycans; physical properties; modulating physical ... See more keywords