Predicting Biomolecular Binding Kinetics: A Review.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.2c01085
Abstract: Biomolecular binding kinetics including the association (kon) and dissociation (koff) rates are critical parameters for therapeutic design of small-molecule drugs, peptides, and antibodies. Notably, the drug molecule residence time or dissociation rate has been shown… read more here.
Keywords: biomolecular binding; dissociation; binding kinetics; kinetics review ... See more keywords
Deep Learning for Predicting Biomolecular Binding Sites of Proteins
Sign Up to like & getrecommendations! Published in 2025 at "Research"
DOI: 10.34133/research.0615
Abstract: The rapid evolution of deep learning has markedly enhanced protein–biomolecule binding site prediction, offering insights essential for drug discovery, mutation analysis, and molecular biology. Advancements in both sequence-based and structure-based methods demonstrate their distinct strengths… read more here.
Keywords: deep learning; learning predicting; sites proteins; biomolecular binding ... See more keywords