Biodegradation of Carbon‐Based Nanomaterials: The Importance of “Biomolecular Corona” Consideration
Sign Up to like & getrecommendations! Published in 2021 at "Advanced Functional Materials"
DOI: 10.1002/adfm.202105649
Abstract: It has been over a decade since oxidative enzymes were first used to degrade carbon‐based nanomaterials (CBNs). Although enormous progress has been achieved in this field, many questions and problems remain unresolved that need to… read more here.
Keywords: based nanomaterials; carbon based; biomolecular corona; biodegradation ... See more keywords
The protein corona on nanoparticles as viewed from a nanoparticle-sizing perspective.
Sign Up to like & getrecommendations! Published in 2018 at "Wiley interdisciplinary reviews. Nanomedicine and nanobiotechnology"
DOI: 10.1002/wnan.1500
Abstract: Most surfaces of engineered nanoparticles (NPs) are reactive toward biomolecules. Therefore, whenever NPs become immersed in biological fluids, proteins and other biomolecules bind to the NP surface, forming an adsorption layer (biomolecular corona) that modifies… read more here.
Keywords: corona; biomolecular corona; nanoparticles viewed; biology ... See more keywords
Brain Targeting by Liposome-Biomolecular Corona Boosts Anticancer Efficacy of Temozolomide in Glioblastoma Cells.
Sign Up to like & getrecommendations! Published in 2018 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.8b00339
Abstract: Temozolomide (TMZ) is the current first-line chemotherapy for treatment of glioblastoma multiforme (GBM). However, similar to other brain therapeutic compounds, access of TMZ to brain tumors is impaired by the blood-brain barrier (BBB) leading to… read more here.
Keywords: brain; biomolecular corona; glioblastoma; efficacy ... See more keywords
Identification of Receptor Binding to the Biomolecular Corona of Nanoparticles.
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DOI: 10.1021/acsnano.6b07933
Abstract: Biomolecules adsorbed on nanoparticles are known to confer a biological identity to nanoparticles, mediating the interactions with cells and biological barriers. However, how these molecules are presented on the particle surface in biological milieu remains… read more here.
Keywords: identification receptor; corona; biomolecular corona; binding biomolecular ... See more keywords
Analysis of nanoparticle biomolecule complexes.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c7nr08696b
Abstract: Nanoparticles exposed to biological fluids adsorb biomolecules on their surface forming a biomolecular corona. This corona determines, on a molecular level, the interactions and impact the newly formed complex has on cells and organisms. The… read more here.
Keywords: nanoparticle biomolecule; corona; nanoparticle; biomolecular corona ... See more keywords
Physiology, pathology and the biomolecular corona: the confounding factors in nanomedicine design.
Sign Up to like & getrecommendations! Published in 2022 at "Nanoscale"
DOI: 10.1039/d1nr08101b
Abstract: The biomolecular corona that forms on nanomedicines in different physiological and pathological environments confers a new biological identity. How the recipient biological system's state can potentially affect nanomedicine corona formation, and how this can be… read more here.
Keywords: corona formation; pathology; physiology; biomolecular corona ... See more keywords
Biomolecular Corona Stability in Association with Plasma Cholesterol Level
Sign Up to like & getrecommendations! Published in 2022 at "Nanomaterials"
DOI: 10.3390/nano12152661
Abstract: Biomolecular corona is spontaneously formed on the surface of nanoparticles (NPs) when they are in contact with biological fluids. It plays an important role in the colloidal stability of NPs, which is of importance for… read more here.
Keywords: level; plasma; biomolecular corona; stability ... See more keywords