Engineering Biomolecular Switches for Dynamic Metabolic Control.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in biochemical engineering/biotechnology"
DOI: 10.1007/10_2016_9
Abstract: Living organisms have been exploited as production hosts for a large variety of compounds. To improve the efficiency of bioproduction, metabolic pathways in an organism are usually manipulated by various genetic modifications. However, bottlenecks during… read more here.
Keywords: engineering; switches dynamic; engineering biomolecular; control ... See more keywords
Programmable biomolecular switches for rewiring flux in Escherichia coli
Sign Up to like & getrecommendations! Published in 2019 at "Nature Communications"
DOI: 10.1038/s41467-019-11793-7
Abstract: Synthetic biology aims to develop programmable tools to perform complex functions such as redistributing metabolic flux in industrial microorganisms. However, development of protein-level circuits is limited by availability of designable, orthogonal, and composable tools. Here,… read more here.
Keywords: switches rewiring; flux; rewiring flux; biomolecular switches ... See more keywords