Ongoing human chromosome end extension revealed by analysis of BioNano and nanopore data
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DOI: 10.1038/s41598-018-34774-0
Abstract: The majority of human chromosome ends remain incompletely assembled due to their highly repetitive structure. In this study, we use BioNano data to anchor and extend chromosome ends from two European trios as well as… read more here.
Keywords: bionano; human chromosome; nanopore data; extension ... See more keywords
Optical Mapping Uncovers Multiple Novel Genomic Structural Variants in Patient Leukemias
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DOI: 10.1182/blood-2020-143175
Abstract: Leukemias are a diverse collection of hematopoietic cancers with limited chemotherapeutic treatment options. Patients unsuitable or unable for bone marrow transplantation have a dismal prognosis. Although previous studies have shown that there are only a… read more here.
Keywords: optical mapping; current employment; bionano; bionano genomics ... See more keywords