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Published in 2021 at "Chemical Science"
DOI: 10.1039/d1sc03812e
Abstract: DNA 5-hydroxymethyluracil (5hmU) is a thymine modification existing in the genomes of various organisms. The post-replicative formation of 5hmU occurs via hydroxylation of thymine by ten-eleven translocation (TET) dioxygenases in mammals and J-binding proteins (JBPs)…
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Keywords:
enzyme mediated;
bioorthogonal labeling;
labeling method;
mediated bioorthogonal ... See more keywords