Improved Protease-Targeting and Biopharmaceutical Properties of Novel Prodrugs of Ganciclovir.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00792
Abstract: The prodrug strategy has been frequently employed as a chemical approach for overcoming the disadvantages of existing parent drugs. In this report, we synthesized four monoester prodrugs of ganciclovir, an anticytomegalovirus drug, and demonstrated their… read more here.
Keywords: ganciclovir prodrugs; hcmv protease; prodrugs ganciclovir; biopharmaceutical properties ... See more keywords
The Flavonoid Components of Scutellaria baicalensis: Biopharmaceutical Properties and their Improvement using Nanoformulation Techniques
Sign Up to like & getrecommendations! Published in 2022 at "Current Topics in Medicinal Chemistry"
DOI: 10.2174/1568026623666221128144258
Abstract: Scutellaria baicalensis georgi, known as “Huangqin” in its dried root form, is a herb widely used in traditional Chinese medicine for “clearing away heat, removing dampness, purging fire and detoxification”. Baicalin, baicalein, wogonin, and wogonoside… read more here.
Keywords: components scutellaria; biopharmaceutical properties; flavonoid components; baicalensis ... See more keywords