Biophysical characterisation of the Bcl-x pre-mRNA and binding specificity of the ellipticine derivative GQC-05: Implication for alternative splicing regulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.943105
Abstract: The BCL2L1 gene expresses two isoforms of Bcl-x protein via the use of either of two alternative 5′ splice sites (5′ss) in exon 2. These proteins have antagonistic actions, Bcl-XL being anti-apoptotic and Bcl-XS pro-apoptotic.… read more here.
Keywords: characterisation bcl; derivative gqc; ellipticine derivative; biophysical characterisation ... See more keywords
Biochemical and Biophysical Characterisation of the Hepatitis E Virus Guanine-7-Methyltransferase
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051505
Abstract: Hepatitis E virus (HEV) is an understudied pathogen that causes infection through fecal contaminated drinking water and is prominently found in South Asian countries. The virus affects ~20 million people annually, leading to ~60,000 infections… read more here.
Keywords: biochemical biophysical; hepatitis virus; biophysical characterisation; mtase ... See more keywords