Biophysical insights from a single chain camelid antibody directed against the Disrupted-in-Schizophrenia 1 protein
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DOI: 10.1371/journal.pone.0191162
Abstract: Accumulating evidence suggests an important role for the Disrupted-in-Schizophrenia 1 (DISC1) protein in neurodevelopment and chronic mental illness. In particular, the C-terminal 300 amino acids of DISC1 have been found to mediate important protein-protein interactions… read more here.
Keywords: protein; chain; antibody; disrupted schizophrenia ... See more keywords
Structural and Biophysical Insights into SPINK1 Bound to Human Cationic Trypsin
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DOI: 10.3390/ijms23073468
Abstract: (1) The serine protease inhibitor Kazal type 1 (SPINK1) inhibits trypsin activity in zymogen granules of pancreatic acinar cells. Several mutations in the SPINK1 gene are associated with acute recurrent pancreatitis (ARP) and chronic pancreatitis… read more here.
Keywords: spink1; biophysical insights; cationic trypsin; human cationic ... See more keywords