An Interpretable Machine-Learning Algorithm to Predict Disordered Protein Phase Separation Based on Biophysical Interactions
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DOI: 10.3390/biom12081131
Abstract: Protein phase separation is increasingly understood to be an important mechanism of biological organization and biomaterial formation. Intrinsically disordered protein regions (IDRs) are often significant drivers of protein phase separation. A number of protein phase… read more here.
Keywords: biophysical interactions; phase separation; protein phase; disordered protein ... See more keywords
Biophysical Interactions Underpin the Emergence of Information in the Genetic Code
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DOI: 10.3390/life13051129
Abstract: The genetic code conceals a ‘code within the codons’, which hints at biophysical interactions between amino acids and their cognate nucleotides. Yet, research over decades has failed to corroborate systematic biophysical interactions across the code.… read more here.
Keywords: amino acids; biophysical interactions; genetic code; emergence ... See more keywords