Ceramide Domains in Health and Disease: A Biophysical Perspective.
Sign Up to like & getrecommendations! Published in 2019 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-3-030-21162-2_6
Abstract: Ceramides are the central molecules in sphingolipid metabolism. In addition, they are recognized as important modulators of cell function, playing key roles in several cellular processes that range from cell proliferation to cell death. Moreover,… read more here.
Keywords: ceramide domains; disease biophysical; domains health; health disease ... See more keywords
Probing the biophysical properties of tumor cells during mitosis by atomic force microscopy
Sign Up to like & getrecommendations! Published in 2018 at "Biomechanics and Modeling in Mechanobiology"
DOI: 10.1007/s10237-018-1012-0
Abstract: Mitosis is an important physiological event accompanying with dramatic changes of cellar biophysical properties. Failure of mitosis results in cell death or chromosome aneuploidy. In this study, we used atomic force microscopy to probe and… read more here.
Keywords: properties tumor; mitosis; microscopy; tumor cells ... See more keywords
Eugenol Nanoencapsulated by Sodium Caseinate: Physical, Antimicrobial, and Biophysical Properties
Sign Up to like & getrecommendations! Published in 2017 at "Food Biophysics"
DOI: 10.1007/s11483-017-9509-0
Abstract: To improve the application of essential oils as natural antimicrobial preservatives, the objective of the present study was to determine physical, antimicrobial, and biophysical properties of eugenol after nanoencapsulation by sodium caseinate (NaCas). Emulsions were… read more here.
Keywords: eugenol; sodium caseinate; physical antimicrobial; biophysical properties ... See more keywords
Exploring the biophysical properties of phytosterols in the plasma membrane for novel cancer prevention strategies.
Sign Up to like & getrecommendations! Published in 2018 at "Biochimie"
DOI: 10.1016/j.biochi.2018.04.028
Abstract: Cancer is a global problem with no sign that incidences are reducing. The great costs associated with curing cancer, through developing novel treatments and applying patented therapies, is an increasing burden to developed and developing… read more here.
Keywords: biology; biophysical properties; cancer; prevention ... See more keywords
Asymmetric glycerophospholipids impart distinctive biophysical properties to lipid bilayers.
Sign Up to like & getrecommendations! Published in 2021 at "Biophysical journal"
DOI: 10.1016/j.bpj.2021.02.046
Abstract: Phospholipids are a diverse group of biomolecules consisting of a hydrophilic head group and two hydrophobic acyl tails. The nature of the head and length and saturation of the acyl tails are important for defining… read more here.
Keywords: properties lipid; impart distinctive; lipid bilayers; biophysical properties ... See more keywords
Biophysical properties and finger print of Boswellia Sp. Burseraceae
Sign Up to like & getrecommendations! Published in 2019 at "Saudi Journal of Biological Sciences"
DOI: 10.1016/j.sjbs.2019.09.019
Abstract: For the first time a finger print analysis via high-performance thin layer chromatography (HPTLC) of Boswellia Sp. Burseraceae was accomplished. A preliminary investigation of the Boswellia Sp. Burseraceae displayed the presence of chemical constituents that… read more here.
Keywords: boswellia burseraceae; biophysical properties; print boswellia; properties finger ... See more keywords
Increased atrial effectiveness of flecainide conferred by altered biophysical properties of sodium channels.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of molecular and cellular cardiology"
DOI: 10.1016/j.yjmcc.2022.01.009
Abstract: Atrial fibrillation (AF) affects over 1% of the population and is a leading cause of stroke and heart failure in the elderly. A feared side effect of sodium channel blocker therapy, ventricular pro-arrhythmia, appears to… read more here.
Keywords: increased atrial; biophysical properties; sodium channel; sodium channels ... See more keywords
Structural Stability and Biophysical Properties of the Mega-Protein Erythrocruorin Are Regulated by Polyethylene Glycol Surface Coverage.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00196
Abstract: A wide variety of hemoglobin-based oxygen carriers (HBOCs) have been designed for use as red blood cell (RBC) substitutes in transfusion medicine, ex vivo organ perfusion, oxygen delivery to hypoxic tissues, and a myriad of… read more here.
Keywords: surface; surface coverage; stability biophysical; biophysical properties ... See more keywords
Alanine Scanning Effects on the Biochemical and Biophysical Properties of Intrinsically Disordered Proteins: A Case Study of the Histidine to Alanine Mutations in Amyloid-β42
Sign Up to like & getrecommendations! Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.8b00926
Abstract: Alanine scanning is a tool in molecular biology that is commonly used to evaluate the contribution of a specific amino acid residue to the stability and function of a protein. Additionally, this tool is also… read more here.
Keywords: alanine; histidine alanine; biochemical biophysical; biophysical properties ... See more keywords
Biophysical and Sequence-Based Methods for Identifying Monovalent and Bivalent Antibodies with High Colloidal Stability.
Sign Up to like & getrecommendations! Published in 2018 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.7b00779
Abstract: In vitro antibody discovery and/or affinity maturation are often performed using antibody fragments (Fabs), but most monovalent Fabs are reformatted as bivalent IgGs (monoclonal antibodies, mAbs) for therapeutic applications. One problem related to reformatting antibodies… read more here.
Keywords: antibody; association; biophysical properties; reformatted bivalent ... See more keywords
Synthesis and Biophysical Properties of Phosphorodiamidate Piperidino Oligomers.
Sign Up to like & getrecommendations! Published in 2023 at "Organic letters"
DOI: 10.1021/acs.orglett.2c04067
Abstract: We report the synthesis of piperidino nucleoside phosphoramidates functionalized with uracil, cytosine, guanine, and adenine and their incorporation into oligomers. High-performance liquid chromatography analyses demonstrated that a phosphorodiamidate piperidino oligomer (PPO) is more lipophilic than… read more here.
Keywords: biophysical properties; piperidino oligomers; phosphorodiamidate piperidino; piperidino ... See more keywords