Thermodynamic and biophysical study of fatty acid effector binding to soybean lipoxygenase: implications for allostery driven by helix α2 dynamics
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DOI: 10.1002/1873-3468.14275
Abstract: Previous comparative kinetic isotope effects have inferred an allosteric site for fatty acids and their derivatives that modulates substrate selectivity in 15‐lipoxygenases. Hydrogen–deuterium exchange also previously revealed regionally defined enhanced protein flexibility, centred at helix… read more here.
Keywords: thermodynamic biophysical; biophysical study; fatty acid; soybean lipoxygenase ... See more keywords