Articles with "bioprocess considerations" as a keyword



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Bioprocess considerations for T‐cell therapy: Investigating the impact of agitation, dissolved oxygen, and pH on T‐cell expansion and differentiation

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Published in 2020 at "Biotechnology and Bioengineering"

DOI: 10.1002/bit.27468

Abstract: Adoptive T‐cell therapy (ACT) has emerged as a promising new way to treat systemic cancers such as acute lymphoblastic leukemia. However, the robustness and reproducibility of the manufacturing process remains a challenge. Here, a single‐use… read more here.

Keywords: cell therapy; bioprocess considerations; differentiation; dissolved oxygen ... See more keywords