Relevance of biopsy-derived pancreatic organoids in the development of efficient transcriptomic signatures to predict adjuvant chemosensitivity in pancreatic cancer
Sign Up to like & getrecommendations! Published in 2021 at "Translational Oncology"
DOI: 10.1016/j.tranon.2021.101315
Abstract: Highlights • Most patient with pancreatic cancer are treated by chemotherapy.• Treatments selection are not personalized on the tumor characteristics.• Signatures predicting chemotherapy efficiency are essential for personalizing treatments.• An RNA signature of gemcitabine-sensitivity is… read more here.
Keywords: relevance biopsy; efficient transcriptomic; transcriptomic signatures; biopsy derived ... See more keywords
Isolation of Biopsy-Derived, Human Cervical Keratinocytes Propagated as Monolayer and Organoid Cultures
Sign Up to like & getrecommendations! Published in 2018 at "Scientific Reports"
DOI: 10.1038/s41598-018-36150-4
Abstract: The successful isolation and propagation of patient-derived keratinocytes from cervical lesions constitute a more appropriate model of cervical disease than traditional cervical cancer-derived cell lines such as SiHa and CaSki. Our aim was to streamline… read more here.
Keywords: isolation biopsy; cervical keratinocytes; isolation; biopsy derived ... See more keywords
Recapitulation of the accessible interface of biopsy-derived canine intestinal organoids to study epithelial-luminal interactions
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0231423
Abstract: Recent advances in canine intestinal organoids have expanded the option for building a better in vitro model to investigate translational science of intestinal physiology and pathology between humans and animals. However, the three-dimensional geometry and… read more here.
Keywords: recapitulation accessible; interface; intestinal organoids; biopsy derived ... See more keywords