LAUSR

Bioreductive dynamic kinetic resolution of ethyl 2-methoxy-3-oxo-3-phenylpropanoate

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0 Published in 2020 at "Catalysis Communications"

DOI: 10.1016/j.catcom.2019.105865

Abstract: Abstract Ketoreductase ChKRED12 from Chryseobacterium sp. CA49 was identified as a highly stereoselective catalyst for the bioreductive production of (2S,3S)-ethyl 3-hydroxy-2-methoxy-3-phenylpropanoate (EMHP) through dynamic kinetic resolution. Its performance was further improved using semi-rational design strategies… read more here.

Keywords: bioreductive dynamic; ethyl; kinetic resolution; methoxy ... See more keywords