Introduction of quorum sensing elements into bacterial bioreporter circuits enhances explosives’ detection capabilities
Sign Up to like & getrecommendations! Published in 2022 at "Engineering in Life Sciences"
DOI: 10.1002/elsc.202100134
Abstract: A possible solution for the standoff detection of buried landmines is based on the use of microbial bioreporters, genetically engineered to emit a remotely detectable optical signal in response to trace amounts of explosives’ signature… read more here.
Keywords: bioreporter; dnt inducible; detection; quorum sensing ... See more keywords
Toxicity Characterization of Environment-Related Pollutants Using a Biospectroscopy-Bioreporter-Coupling Approach: Potential for Real-World Toxicity Determination and Source Apportionment of Multiple Pollutants.
Sign Up to like & getrecommendations! Published in 2023 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c03908
Abstract: Exposure to environmental pollutants occurs ubiquitously and poses many risks to human health and the ecosystem. Although many analytical methods have been developed to assess such jeopardies, the circumstances applying these means are restricted to… read more here.
Keywords: bioreporter; toxicity; bioreporter coupling; biospectroscopy bioreporter ... See more keywords
Improving Estrogenic Compound Screening Efficiency by Using Self-Modulating, Continuously Bioluminescent Human Cell Bioreporters Expressing a Synthetic Luciferase
Sign Up to like & getrecommendations! Published in 2019 at "Toxicological Sciences"
DOI: 10.1093/toxsci/kfz004
Abstract: A synthetic bacterial luciferase-based autobioluminescent bioreporter, HEK293ERE/Gal4-Lux, was developed in a human embryonic kidney (HEK293) cell line for the surveillance of chemicals displaying endocrine disrupting activity. Unlike alternative luminescent reporters, this bioreporter generates bioluminescence autonomously… read more here.
Keywords: cell; hek293ere gal4; gal4 lux; human cell ... See more keywords
Sense and sensibility: of synthetic biology and the redesign of bioreporter circuits
Sign Up to like & getrecommendations! Published in 2021 at "Microbial Biotechnology"
DOI: 10.1111/1751-7915.13955
Abstract: It is tempting to speculate that sixty years ago, when Jacob and Monod presented their model of the lac operon (Jacob and Monod, 1961), they already had a glimpse of the future of the lacZ… read more here.
Keywords: bioreporter; reporter gene; engineering; synthetic biology ... See more keywords
Enhancing DNT Detection by a Bacterial Bioreporter: Directed Evolution of the Transcriptional Activator YhaJ
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.821835
Abstract: Detection of buried landmines is a dangerous and complicated task that consumes large financial resources and poses significant risks to the personnel involved. A potential alternative to conventional detection methodologies is the use of microbial… read more here.
Keywords: bioreporter directed; bioreporter; detection; directed evolution ... See more keywords