Cardiac Disease Alters Myocardial Tissue Levels of Epoxyeicosatrienoic Acids and Key Proteins Involved in Their Biosynthesis and Degradation
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DOI: 10.3390/ijms232012433
Abstract: CYP2J2 is the main epoxygenase in the heart that is responsible for oxidizing arachidonic acid to cis-epoxyeicosatrienoic acids (EETs). Once formed, EETs can then be hydrolyzed by soluble epoxide hydrolase (sEH, encoded by EPHX2) or… read more here.
Keywords: biosynthesis degradation; involved biosynthesis; epoxyeicosatrienoic acids; tissue ... See more keywords