The synergy between nucleotide biosynthesis inhibitors and antiviral nucleosides: New opportunities against viral infections?
Sign Up to like & getrecommendations! Published in 2022 at "Archiv der Pharmazie"
DOI: 10.1002/ardp.202200217
Abstract: 5'-Phosphorylated nucleoside derivatives are molecules that can be found in all living organisms and viruses. Over the last century, the development of structural analogs that could disrupt the transcription and translation of genetic information culminated… read more here.
Keywords: inhibitors antiviral; nucleotide biosynthesis; biosynthesis inhibitors; antiviral nucleosides ... See more keywords
Novel leukotriene biosynthesis inhibitors (2012-2016) as anti-inflammatory agents
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DOI: 10.1080/13543776.2017.1276568
Abstract: ABSTRACT Introduction: Leukotrienes (LTs) are lipid mediators produced from arachidonic acid with a broad variety of bioactivities in allergy and inflammation. The biosynthesis of LTs mainly involves 5-lipoxygenase (5-LO) and its 5-lipoxygenase-activating protein (FLAP), LTA4… read more here.
Keywords: biosynthesis inhibitors; ltc4 synthase; biosynthesis; hydrolase ltc4 ... See more keywords