Enhanced Biosynthesis Performance of Heterologous Proteins in CHO-K1 Cells Using CRISPR-Cas9.
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DOI: 10.1021/acssynbio.7b00375
Abstract: Chinese hamster ovary (CHO) cells are the famous expression system for industrial production of recombinant proteins, such as therapeutic antibodies. However, there still remain bottlenecks in protein quality and weakness in expression efficiency because of… read more here.
Keywords: biosynthesis performance; crispr cas9; cho cells; enhanced biosynthesis ... See more keywords