Mechanistic Understanding of Lanthipeptide Biosynthetic Enzymes
Sign Up to like & getrecommendations! Published in 2017 at "Chemical Reviews"
DOI: 10.1021/acs.chemrev.6b00591
Abstract: Lanthipeptides are ribosomally synthesized and post-translationally modified peptides (RiPPs) that display a wide variety of biological activities, from antimicrobial to antiallodynic. Lanthipeptides that display antimicrobial activity are called lantibiotics. The post-translational modification reactions of lanthipeptides… read more here.
Keywords: understanding lanthipeptide; lanthipeptide biosynthetic; post translational; mechanistic understanding ... See more keywords
Redirecting RiPP Biosynthetic Enzymes to Proteins and Backbone-Modified Substrates
Sign Up to like & getrecommendations! Published in 2022 at "ACS Central Science"
DOI: 10.1021/acscentsci.1c01577
Abstract: Ribosomally synthesized and post-translationally modified peptides (RiPPs) are peptide-derived natural products that include the FDA-approved analgesic ziconotide1,2 as well as compounds with potent antibiotic, antiviral, and anticancer properties.3 RiPP enzymes known as cyclodehydratases and dehydrogenases… read more here.
Keywords: backbone modified; biosynthetic enzymes; enzymes proteins; redirecting ripp ... See more keywords
In vitro prototyping and rapid optimization of biosynthetic enzymes for cell design
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DOI: 10.1038/s41589-020-0559-0
Abstract: The design and optimization of biosynthetic pathways for industrially relevant, non-model organisms is challenging due to transformation idiosyncrasies, reduced numbers of validated genetic parts and a lack of high-throughput workflows. Here we describe a platform… read more here.
Keywords: vitro prototyping; prototyping rapid; optimization; biosynthetic enzymes ... See more keywords
Localization of the glucosinolate biosynthetic enzymes reveals distinct spatial patterns for the biosynthesis of indole and aliphatic glucosinolates.
Sign Up to like & getrecommendations! Published in 2018 at "Physiologia plantarum"
DOI: 10.1111/ppl.12672
Abstract: Glucosinolates constitute the primary defense metabolites in Arabidopsis thaliana (Arabidopsis). Indole and aliphatic glucosinolates, biosynthesized from tryptophan and methionine, respectively, are known to serve distinct biological functions. Although all genes in the biosynthetic pathways are… read more here.
Keywords: enzymes reveals; localization glucosinolate; glucosinolate biosynthetic; indole aliphatic ... See more keywords
Small Molecule Regulators Targeting NAD+ Biosynthetic Enzymes.
Sign Up to like & getrecommendations! Published in 2021 at "Current medicinal chemistry"
DOI: 10.2174/0929867328666210531144629
Abstract: Nicotinamide adenine dinucleotide (NAD+) is a key player in many metabolic pathways as an activated carrier of electrons. In addition to being the cofactor for redox reactions, NAD+ also serves as the substrate for various… read more here.
Keywords: nad biosynthetic; molecule regulators; small molecule; targeting nad ... See more keywords
Starch content and activities of starch biosynthetic enzymes in wheat, rice and millets
Sign Up to like & getrecommendations! Published in 2020 at "Phytopathology"
DOI: 10.22271/phyto.2020.v9.i4q.11883
Abstract: The aim of the study was to correlate the accumulation of amylose and total starch with activities of starch biosynthetic enzymes (AGPase, SSS and GBSS) in cereals like rice (PB-2, PD-19), wheat (UP-262, PBW-343) and… read more here.
Keywords: starch biosynthetic; activities starch; agpase; biosynthetic enzymes ... See more keywords
Transcriptional Regulators of Ecdysteroid Biosynthetic Enzymes and Their Roles in Insect Development
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.823418
Abstract: Steroid hormones are responsible for coordinating many aspects of biological processes in most multicellular organisms, including insects. Ecdysteroid, the principal insect steroid hormone, is biosynthesized from dietary cholesterol or plant sterols. In the last 20… read more here.
Keywords: roles insect; biosynthetic enzymes; enzymes roles; ecdysteroid biosynthetic ... See more keywords
Production and stably maintenance of strigolactone by transient expression of biosynthetic enzymes in Nicotiana benthamiana
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.1027004
Abstract: Strigolactones (SLs) are phytohormones that play an essential role in plant–microbe interactions. The instability of SLs makes it challenging to use them for application to agriculture. In this study, we successfully produced a large amount… read more here.
Keywords: biosynthetic enzymes; production stably; stably maintenance; nicotiana benthamiana ... See more keywords