Articles with "biosynthetic potential" as a keyword



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Diversity, Antimicrobial Activity, and Biosynthetic Potential of Cultivable Actinomycetes Associated with Lichen Symbiosis

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Published in 2017 at "Microbial Ecology"

DOI: 10.1007/s00248-017-0972-4

Abstract: Lichens are structured associations of a fungus with a cyanobacteria and/or green algae in a symbiotic relationship, which provide specific habitats for diverse bacterial communities, including actinomycetes. However, few studies have been performed on the… read more here.

Keywords: activity biosynthetic; biosynthetic potential; diversity; antimicrobial activity ... See more keywords
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Mining and unearthing hidden biosynthetic potential

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Published in 2021 at "Nature Communications"

DOI: 10.1038/s41467-021-24133-5

Abstract: Genetically encoded small molecules (secondary metabolites) play eminent roles in ecological interactions, as pathogenicity factors and as drug leads. Yet, these chemical mediators often evade detection, and the discovery of novel entities is hampered by… read more here.

Keywords: unearthing hidden; mining unearthing; mining; biosynthetic potential ... See more keywords
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Non-ribosomal peptide biosynthetic potential of the nematode symbiont Photorhabdus.

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Published in 2022 at "Environmental microbiology reports"

DOI: 10.1111/1758-2229.13118

Abstract: Photorhabdus, the symbiotic bacteria of Heterorhabditis nematodes, has been reported to possess many non-ribosomal peptide synthetase (NRPS) biosynthesis gene clusters (BGCs). To provide an in-depth assessment of the non-ribosomal peptide biosynthetic potential of Photorhabdus, we… read more here.

Keywords: biosynthetic potential; photorhabdus; non ribosomal; ribosomal peptide ... See more keywords
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Biosynthetic Potential of the Endophytic Fungus Helotiales sp. BL73 Revealed via Compound Identification and Genome Mining

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Published in 2022 at "Applied and Environmental Microbiology"

DOI: 10.1128/aem.02510-21

Abstract: Endophytic fungi represent an as yet underexplored source of secondary metabolites, of which some may have industrial and medical applications. We isolated a slow-growing fungus belonging to the order Helotiales from the traditional medicinal plant… read more here.

Keywords: genome mining; endophytic fungi; potential endophytic; biosynthetic potential ... See more keywords
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A Genomic Survey of the Natural Product Biosynthetic Potential of Actinomycetes Isolated from New Zealand Lichens

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Published in 2023 at "mSystems"

DOI: 10.1128/msystems.01030-22

Abstract: Lichens are home to complex and distinctive microbial cohorts that have not been extensively explored for the ability to produce novel secondary metabolites. Here, we isolate and obtain genome sequence data for 322 actinomycetes from… read more here.

Keywords: genomic survey; biosynthetic potential; new zealand; secondary metabolites ... See more keywords
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Diversity, Antimicrobial Capabilities, and Biosynthetic Potential of Mangrove Actinomycetes from Coastal Waters in Pahang, Malaysia

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Published in 2018 at "Journal of Coastal Research"

DOI: 10.2112/si82-025.1

Abstract: ABSTRACT Zainal Abidin, Z.A.; Chowdhury, A.J.K.; Abdul Malek, N., and Zainuddin, Z., 2018. Diversity, antimicrobial capabilities, and biosynthetic potential of mangrove actinomycetes from coastal waters in Pahang, Malaysia. In: Ashraf, M.A. and Chowdhury, A.J.K. (eds.),… read more here.

Keywords: biosynthetic potential; antimicrobial capabilities; mangrove actinomycetes; potential mangrove ... See more keywords
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A symbiotic bacterium of Antarctic fish reveals environmental adaptability mechanisms and biosynthetic potential towards antibacterial and cytotoxic activities

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Published in 2023 at "Frontiers in Microbiology"

DOI: 10.3389/fmicb.2022.1085063

Abstract: Antarctic microbes are important agents for evolutionary adaptation and natural resource of bioactive compounds, harboring the particular metabolic pathways to biosynthesize natural products. However, not much is known on symbiotic microbiomes of fish in the… read more here.

Keywords: symbiotic bacterium; antarctic fish; biosynthetic potential; bacterium antarctic ... See more keywords
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Biosynthetic Potential of Streptomyces Rationalizes Genome-Based Bioprospecting

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Published in 2021 at "Antibiotics"

DOI: 10.3390/antibiotics10070873

Abstract: Streptomyces are the most prolific source of structurally diverse microbial natural products. Advancing genome-based analysis reveals the previously unseen potential of Streptomyces to produce numerous novel secondary metabolites, which allows us to take natural product… read more here.

Keywords: biosynthetic potential; potential streptomyces; genome based; streptomyces rationalizes ... See more keywords

Revealing Genome-Based Biosynthetic Potential of Streptomyces sp. BR123 Isolated from Sunflower Rhizosphere with Broad Spectrum Antimicrobial Activity

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Published in 2022 at "Antibiotics"

DOI: 10.3390/antibiotics11081057

Abstract: Actinomycetes, most notably the genus Streptomyces, have great importance due to their role in the discovery of new natural products, especially for finding antimicrobial secondary metabolites that are useful in the medicinal science and biotechnology… read more here.

Keywords: antimicrobial activity; biosynthetic potential; genome based; genome ... See more keywords
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Diversity and Biosynthetic Potential of Fungi Isolated from St. John’s Island, Singapore

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Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24021033

Abstract: Adaptation to a wide variety of habitats allows fungi to develop unique abilities to produce diverse secondary metabolites with diverse bioactivities. In this study, 30 Ascomycetes fungi isolated from St. John’s Island, Singapore were investigated… read more here.

Keywords: fungi isolated; biosynthetic potential; isolated john; island singapore ... See more keywords
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Biosynthetic Potential of Hypogymnia Holobionts: Insights into Secondary Metabolite Pathways

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Published in 2023 at "Journal of Fungi"

DOI: 10.3390/jof9050546

Abstract: Lichens are symbiotic associations consisting of a photobiont (algae or cyanobacteria) and a mycobiont (fungus). They are known to produce a variety of unique secondary metabolites. To access this biosynthetic potential for biotechnological applications, deeper… read more here.

Keywords: lichen; biosynthetic potential; hypogymnia; biosynthetic gene ... See more keywords