Treating Clostridioides difficile: Could Microbiota-based Live Biotherapeutic Products Provide the Answer?
Sign Up to like & getrecommendations! Published in 2023 at "Infection and Drug Resistance"
DOI: 10.2147/idr.s400570
Abstract: Abstract Clostridioides difficile infection (CDI) is a pressing health care issue due to the limited effectiveness of current treatments and high recurrence rates. Current available antibiotic options for CDI disrupt the fecal microbiome which predisposes… read more here.
Keywords: live biotherapeutic; clostridioides difficile; microbiota based; based live ... See more keywords
Microbiome engineering: engineered live biotherapeutic products for treating human disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.1000873
Abstract: The human microbiota is implicated in many disease states, including neurological disorders, cancer, and inflammatory diseases. This potentially huge impact on human health has prompted the development of microbiome engineering methods, which attempt to adapt… read more here.
Keywords: engineered live; live biotherapeutic; biotherapeutic products; microbiome ... See more keywords
Live Biotherapeutic Products, A Road Map for Safety Assessment
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2020.00237
Abstract: Recent developments in the understanding of the relationship between the microbiota and its host have provided evidence regarding the therapeutic potential of selected microorganisms to prevent or treat disease. According to Directive 2001/83/EC, in the… read more here.
Keywords: safety assessment; biotherapeutic products; live biotherapeutic; safety ... See more keywords