Articles with "biotin moiety" as a keyword



Potent Platinum(IV) Prodrugs That Incorporate a Biotin Moiety to Selectively Target Cancer Cells

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Published in 2022 at "Pharmaceutics"

DOI: 10.3390/pharmaceutics14122780

Abstract: Four platinum(IV) prodrugs incorporating a biotin moiety to selectively target cancer cells were synthesised, characterised, and their biological activity assessed. All complexes exhibited exceptional in vitro cytotoxicity against a panel of cancer cell lines, with… read more here.

Keywords: cancer; platinum prodrugs; biotin moiety; platinum ... See more keywords