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Published in 2021 at "Nature Communications"
DOI: 10.1038/s41467-021-22360-4
Abstract: Biotin is an essential micro-nutrient across the three domains of life. The paradigm earlier step of biotin synthesis denotes “BioC-BioH” pathway in Escherichia coli. Here we report that BioZ bypasses the canonical route to begin…
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Keywords:
synthesis pathway;
biotin synthesis;
bioz;
synthesis ... See more keywords
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Published in 2022 at "PLoS Pathogens"
DOI: 10.1371/journal.ppat.1010615
Abstract: Tuberculosis (TB) is one of the leading infectious diseases of global concern, and one quarter of the world’s population are TB carriers. Biotin metabolism appears to be an attractive anti-TB drug target. However, the first-stage…
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Keywords:
biotin synthesis;
bioh;
drug target;
anti drug ... See more keywords