Reconnoitring the antioxidant and anti-bacterial potential of different fruits after tannin acyl hydrolase mediated biotransformation.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and applied biochemistry"
DOI: 10.1002/bab.2461
Abstract: Condensed and hydrolyzable tannins are secondary metabolites present in almost every plant part.Tannase enzyme acts on hydrolyzable tannins to produce gallic acid and tannase- mediated end-products with immense therapeutic potential. Seven different fruits with significant… read more here.
Keywords: anti bacterial; hydrolyzable tannins; biotransformation; increase anti ... See more keywords
Effect of HepG2 cell 3D cultivation on the metabolism of the anabolic androgenic steroid metandienone.
Sign Up to like & getrecommendations! Published in 2023 at "Drug testing and analysis"
DOI: 10.1002/dta.3455
Abstract: The elucidation of the metabolic fate of prohibited substances is crucial for the abuse detection. The human hepatocyte cell line HepG2 can be used to study biotransformation. In order to improve this in vitro model… read more here.
Keywords: cell; cultivation; biotransformation; anabolic androgenic ... See more keywords
In vitro to in vivo extrapolation of biotransformation rates for assessing bioaccumulation of hydrophobic organic chemicals in mammals.
Sign Up to like & getrecommendations! Published in 2017 at "Environmental toxicology and chemistry"
DOI: 10.1002/etc.3718
Abstract: Incorporating biotransformation in bioaccumulation assessments of hydrophobic chemicals in both aquatic and terrestrial organisms in a simple, rapid, and cost-effective manner is urgently needed to improve bioaccumulation assessments of potentially bioaccumulative substances. One approach to… read more here.
Keywords: rate constants; extrapolation; biotransformation; hydrophobic ... See more keywords
Models Used to Predict Chemical Bioaccumulation in Fish from in Vitro Biotransformation Rates Require Accurate Estimates of Blood–Water Partitioning and Chemical Volume of Distribution
Sign Up to like & getrecommendations! Published in 2022 at "Environmental Toxicology and Chemistry"
DOI: 10.1002/etc.5503
Abstract: Methods for extrapolating measured in vitro intrinsic clearance to a whole‐body biotransformation rate constant (kB) have been developed to support modeled bioaccumulation assessments for fish. The inclusion of extrapolated kB values into existing bioaccumulation models… read more here.
Keywords: predict chemical; volume distribution; biotransformation; used predict ... See more keywords
Biotransformation of cholesterol and 16,17‐alpha epoxypregnenolone by novel Cladosporium sp. strain IS547
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.201600191
Abstract: Nowadays, there are a few steroid drugs or intermediates that have been obtained via the transformation of microorganisms, and many strains of transformed steroids have not been found yet. Therefore, it is very significant to… read more here.
Keywords: alpha epoxypregnenolone; cladosporium; cholesterol; transformation ... See more keywords
Statistically optimized ceftriaxone sodium biotransformation through Achromobacter xylosoxidans strain Cef6: an unusual insight for bioremediation
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Basic Microbiology"
DOI: 10.1002/jobm.201700497
Abstract: The present study underlines a unique promising approach toward efficient biotransformation of ceftriaxone sodium (Ceftx), a highly frequent prescribed cephalosporin antibiotic, by a newly bacterium namely Achromobacter xylosoxidans strain Cef6 isolated from Ceftx contaminated raw… read more here.
Keywords: ceftx; achromobacter xylosoxidans; strain cef6; ceftriaxone sodium ... See more keywords
Molecular Mechanisms, Characterization Methods, and Utilities of Nanoparticle Biotransformation in Nanosafety Assessments.
Sign Up to like & getrecommendations! Published in 2020 at "Small"
DOI: 10.1002/smll.201907663
Abstract: It is a big challenge to reveal the intrinsic cause of a nanotoxic effect due to diverse branches of signaling pathways induced by engineered nanomaterials (ENMs). Biotransformation of toxic ENMs involving biochemical reactions between nanoparticles… read more here.
Keywords: mechanisms characterization; methods utilities; biotransformation; molecular mechanisms ... See more keywords
Studying the Biotransformation of Phosphorothioate-Containing Oligonucleotide Drugs by LC-MS.
Sign Up to like & getrecommendations! Published in 2019 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-9670-4_18
Abstract: Across the pharmaceutical industry, there is increasing interest and need to investigate the biotransformation of oligonucleotide drugs. The method of choice is high-resolution mass spectrometry due to its unmet sensitivity and specificity.Here, we describe a… read more here.
Keywords: studying biotransformation; containing oligonucleotide; oligonucleotide drugs; phosphorothioate containing ... See more keywords
Fungi from industrial tannins: potential application in biotransformation and bioremediation of tannery wastewaters
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-8876-x
Abstract: Tannins are a complex family of polyphenolic compounds, widely distributed in the plant kingdom where they act as growth inhibitors towards many microorganisms including bacteria, yeasts, and fungi. Tannins are one of the major components… read more here.
Keywords: tannery wastewaters; bioremediation tannery; fungi industrial; biotransformation ... See more keywords
Effect of PelB signal sequences on Pfe1 expression and ω-hydroxyundec-9-enoic acid biotransformation in recombinant Escherichia coli
Sign Up to like & getrecommendations! Published in 2018 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-018-9139-6
Abstract: Abstractω-Hydroxyundec-9-enoic acid (ω-HUA) was reported as a valuable medium-chain fatty acid with industrial potentials. For bioconversion of ricinoleic acid to ω-HUA, in this study, an alcohol dehydrogenase (Adh) from Micrococcus luteus, a Baeyer-Villiger monooxygenase (BVMO)… read more here.
Keywords: escherichia coli; enoic acid; coli; biotransformation ... See more keywords
Efficient biotransformation of vitamin D3 to 25-hydroxyvitamin D3 by a newly isolated Bacillus cereus strain
Sign Up to like & getrecommendations! Published in 2019 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-019-10250-1
Abstract: Abstract25-hydroxyvitamin D3 has attracted considerable attention due to its great medical value and huge market demand in animal husbandry. Microbial production of 25-hydroxyvitamin D3 has been recognized as an alternative superior to traditional chemical synthesis.… read more here.
Keywords: hydroxyvitamin; bacillus cereus; biotransformation; vitamin ... See more keywords