Unified biomimetic assembly of voacalgine A and bipleiophylline via divergent oxidative couplings.
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DOI: 10.1038/nchem.2735
Abstract: Bipleiophylline is a highly complex monoterpene indole alkaloid composed of two pleiocarpamine units anchored on an aromatic spacer platform. The synthesis of bipleiophylline is considered as a mountain to climb by the organic chemistry community.… read more here.
Keywords: unified biomimetic; voacalgine bipleiophylline; chemistry; biomimetic assembly ... See more keywords
N-Iodosuccinimide-Mediated Oxidative Coupling of Indoles and Phenols: A Synthetic Study toward the Benzofuroindoline Moiety of Bipleiophylline
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DOI: 10.1055/s-0036-1592002
Abstract: We report our efforts to apply an N-iodosuccinimide-mediated dearomative oxidative coupling of indoles and phenols to benzofuroindoline-containing polycyclic scaffolds related to the natural product bipleiophylline. Suitable conditions from N-substituted indoles are developed and applied to… read more here.
Keywords: indoles phenols; iodosuccinimide mediated; coupling indoles; oxidative coupling ... See more keywords