CircCAMSAP1 promotes non-small cell lung cancer proliferation and inhibits cell apoptosis by sponging miR-1182 and regulating BIRC5
Sign Up to like & getrecommendations! Published in 2022 at "Bioengineered"
DOI: 10.1080/21655979.2021.2011639
Abstract: ABSTRACT Recently, various studies have suggested that circular RNAs (circRNAs) are ubiquitous in various malignant events, including non-small cell lung cancer (NSCLC) and are closely related to cell proliferation and apoptosis. Unfortunately, the molecular functions… read more here.
Keywords: cell; circcamsap1; proliferation; mir 1182 ... See more keywords
Potential Involvement of BIRC5 in Maintaining Pluripotency and Cell Differentiation of Human Stem Cells
Sign Up to like & getrecommendations! Published in 2019 at "Oxidative Medicine and Cellular Longevity"
DOI: 10.1155/2019/8727925
Abstract: The BIRC5 gene encodes a survivin protein belonging to class III of inhibitors of apoptosis, IAP. This protein serves a dual role. First, it regulates cell death, and second, it is an important regulator of… read more here.
Keywords: cell; expression; birc5; stem ... See more keywords
Abstract 6242: Inhibition of BIRC5/survivin by LQZ-7I inhibits neuroblastoma growth while hemizygosity of BIRC5 does not: implications for therapy of neuroblastoma
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-6242
Abstract: Overexpression of survivin, a crucial regulator of the mitotic spindle checkpoint, is associated with poor prognosis in neuroblastoma (NB). Transcriptional inhibitors of survivin have been tested in clinical trials. However, results have been disappointing. We… read more here.
Keywords: lqz s12; growth; survivin; mice ... See more keywords
BIRC5 regulates inflammatory tumor microenvironment-induced aggravation of penile cancer development in vitro and in vivo
Sign Up to like & getrecommendations! Published in 2022 at "BMC Cancer"
DOI: 10.1186/s12885-022-09500-9
Abstract: Background Baculoviral IAP repeat containing 5 (BIRC5) is overexpressed and plays as a key regulator in the progression of various human carcinomas. The inflammatory tumor microenvironment (ITM) is closely associated with the development of cancers.… read more here.
Keywords: inflammatory tumor; development; birc5; tumor microenvironment ... See more keywords
Exploring the role of survivin in neuroendocrine neoplasms
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DOI: 10.18632/oncotarget.27631
Abstract: Neuroendocrine tumors (NETs) are a heterogenous group of tumors. While most NETs have excellent prognosis, certain subsets have aggressive biology and have limited treatment options. We explored the role of survivin in NET as a… read more here.
Keywords: role survivin; birc5; expression; radiation ... See more keywords
Long non-coding RNA SNHG3 promotes the progression of clear cell renal cell carcinoma via regulating BIRC5 expression
Sign Up to like & getrecommendations! Published in 2021 at "Translational Cancer Research"
DOI: 10.21037/tcr-21-1802
Abstract: Background Research has shown that the progression of clear cell renal cell carcinoma (ccRCC) is modulated by long non-coding RNAs (lncRNAs). However, the roles of specific lncRNAs in the malignancy of ccRCC are still unknown.… read more here.
Keywords: expression; progression clear; snhg3; cell ... See more keywords
RFWD3 Participates in the Occurrence and Development of Colorectal Cancer via E2F1 Transcriptional Regulation of BIRC5
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2021.675356
Abstract: Objectives: Colorectal cancer (CRC) is one of the most common human malignancies. It was reported that the alterations in the DNA damage response (DDR) pathways are emerging as novel targets for treatment across different cancer… read more here.
Keywords: rfwd3; colorectal cancer; birc5; crc ... See more keywords
The N6-Methylandenosine-Related Gene BIRC5 as a Prognostic Biomarker Correlated With Cell Migration and Immune Cell Infiltrates in Low Grade Glioma
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Molecular Biosciences"
DOI: 10.3389/fmolb.2022.773662
Abstract: Gliomas account for 75% of all primary malignant brain tumors in adults and are associated with high mortality. Emerging evidence has demonstrated that baculoviral inhibitor of apoptosis repeat containing 5 (BIRC5) plays a critical role… read more here.
Keywords: cell; grade; immune; birc5 ... See more keywords
Prognostic Significance of BIRC5/Survivin in Breast Cancer: Results from Three Independent Cohorts
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DOI: 10.3390/cancers13092209
Abstract: Simple Summary Survivin, coded by the BIRC5 gene, is the cell death preventing protein, which is important for cell division in normal and cancer cells. It is intensively studied as a cancer biomarker and target… read more here.
Keywords: survivin; breast cancer; birc5; cancer ... See more keywords
The Prognostic and Therapeutic Implications of the Chemoresistance Gene BIRC5 in Triple-Negative Breast Cancer
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DOI: 10.3390/cancers14215180
Abstract: Simple Summary TNBC is the most aggressive type of breast cancer affecting women worldwide, and chemoresistance poses a significant clinical challenge associated with a poor prognosis. The molecular mechanisms causing this treatment resistance in TNBC… read more here.
Keywords: gene; tnbc patients; tnbc; birc5 ... See more keywords
Antiapoptotic Gene Genotype and Allele Variations and the Risk of Lymphoma
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DOI: 10.3390/cancers15041012
Abstract: Simple Summary The results of prior studies on the genotypes and allele variations of the antiapoptotic gene and the risk of lymphoma are unclear. To address this gap, this case–control study included 205 Saudi patients,… read more here.
Keywords: antiapoptotic gene; birc5; risk lymphoma; allele variations ... See more keywords